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CURRICULUM VITAE

Name: Makkar, Raj M.D.

Personal History: 127 S. San Vicente Blvd., Suite A3600Los Angeles, CA 90048Business Phone: (310) 423-3977Business Fax: (310) 423-0106

Current Title: Professor of Medicine, UCLA David Geffen School of MedicineDirector, Interventional Cardiology and Cardiac Cath LabAssociate Director of the Heart Institute (Interventional Technologies)Cedars-Sinai Medical Center

Education:1981-1987 MB, BS Gujarat University, India1987-1990 Resident, KM School of PG Medicine and Research

Ahmedabad, India1990-1992 Resident, Detroit Medical Center, Wayne State

University, MI 1992-1993 Chief Medical Resident, Harper Hospital, Wayne State

University, Detroit, MI.1992 Research internship in Laser Laboratory under

Dr. Richard Spears at Wayne State University, Detroit, MI.

1993-1996 Fellow in Cardiology, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles,

CA.1996-1997 Interventional Cardiology/Post-Doctoral

Research Fellow. Cedars-Sinai Medical Center. UCLA School of Medicine.

Licensures:Medical Board of California - #A051998Medical Board of Michigan

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Board Certification:1991 FLEX1992 American Board of Internal Medicine1996 American Board of Internal Medicine, Cardiovascular Disease1999 American Board of Interventional Cardiology

Professional Experience:2010 – Present Director, Interventional Cardiology and Cardiac Cath Lab

Associate Director of the Heart Institute (Interventional Technologies)Cedars-Sinai Medical Center

2006-Present Director, Interventional CardiologyCedars-Sinai Medical Center

2000-Present Director, Cardiovascular Intervention Center, Cedars-Sinai Medical Center

1997-Present Co-Director, Interventional Cardiology Research Program, CVIC, Cedars-Sinai Medical Center

Professional Activities: Professional associations: American College of Cardiology. American Heart Association. Council of vascular thrombosis. Heart Failure Society of America Manuscript reviewer:

LancetJournal of the American College of CardiologyCirculationJournal of Interventional CardiologyCardiac Catheterization and DiagnosisInternational Journal of Cardiology

Editorial Board Member:Journal of American College of Cardiology

Consulting Services:CONOR Medysystems, Inc. Guidant Corp.Medtronic IncCordis (Johnson & Johnson)Sanofi-AventisSt. Jude MedicalSavacor Inc.Edwards LifesciencesMedicines Co.

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CSMC Professional Activitites:Cardiology PICSTEMI Task Force

Honors and Special Awards: Elected by his peers for inclusion in Best Doctors in America® from 2009 to 2016 Stephen R. Corday Chair in Interventional Cardiology, 2010 Chairman, Young Investigator Awards, American College of Cardiology Sessions,

2006 Judge, Young Investigator Awards, American College of Cardiology Sessions,

2004, 2005 First Prize for outstanding research in basic cardiovascular disease at Young

Investigator's Award meeting of American College of Angiology 1997. Second Prize for clinical cardiovascular research at American Heart Association

Lavern Titus Young Investigator’s Award competition for 1998 Elliot Corday Fellow for the year 1993-94. Member, Deans Medical Council, Wayne State University School of Medicine,

1992. Ranked 5th among 320 students in final Medical School Exams. Ranked First in written exams for final M.D. year in university. Honors in Physiology, Medicine and Gynecology in Medical School. Consistent Honors evaluation by faculty at Wayne State University.

Research Grants and Fellowships Received:

1. AHA-WSA Post-doctoral fellowship 1996-1998 $80,000Mechanisms

2. AHA-WSA 1159 GI1 7/1/98-6/30/02 $165,000Brachytherapy, Stent Thrombosis and Restenosis The major goal of this project is to study the effect of radiation alone and in combination with antiplatelet agents on stent related thrombosis and restenosis.Role: Principal Investigator

3. Cedars-Sinai Research Institute Award 1998 $45,000To study the effects of monoclonal antibody to Glycoprotein IIb-IIIa receptor on stent thrombosis and restenosis.

4. Spectranetics Corporation $60,000 Effects of excimer laser angioplasty on stent restenosis in porcine model of stent restenosis.Role: Principal Investigator

5. NIH-NHLBI HL53226 $350,000 Stent regulation of the vascular microenvironment.Role: Co-Investigator (PI: Neal Eigler)

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6. US Surgical 9/1/99 – 8/31/00 $60,000Trial of beta radiation delivery system to prevent stent restenosis (RADIANT Trial). Role: Co-Principal Investigator

7. SmithKline Beecham Pharmaceuticals. 4/1/00 – 3/31/01 $8,000Prevention of restenosis with tranilast and its outcomes: a placebo-controlled trial. Role: Principal Investigator

8. Radiance Medical Systems 12/1/99 – 11/30/00.The beta radiation to reduce in-stent restenosis study (BRITE Trial).

9. NMT Medical, Inc. $27,000 7/1/02-6/30/03 Evaluation of CardioSEAL™ and CardioSEAL STARFlex™ Septal Occlusion Systems in a Porcine ModelThe goal of this project is to test a new device (and modifications of the device) that can be deployed percutaneously to close a defect in the atrial septum.Role: Co-Investigator

10. Savacor, Inc. 9/1/02-8/31/04 $28,942Acute and Chronic Animal Evaluation of the HeartPOD™ Intraatrial Electronic Device in the Porcine ModelThe goal of this project is to develop and test a new device designed to assist with the medical management of chronic heart failure. The device can be inserted permanently in the intraatrial septum surgically or percutaneously.Role: Co-investigator

11. Conor Medsystems, Inc. 7/1/98-3/31/04 $290,980 Conor Stent Coronary Restenosis StudyThe goal of this project is to develop and test a coronary stent with the capability of local drug delivery in order to prevent in-stent restenosis.Role: Co-investigator

12. Osiris Therapeutics, Inc. 5/1/01-4/30/03 $163,029Evaluation of Alternative Routes for Stem Cell Injections in Diseased MyocardiumThe purpose of the study is to assess the viability of injected stem cells into damaged heart muscle via four different methods and then to study the effects of these cells on animal models for heart attacks and cardiomyopathy.Role: Principal investigator

13. Macropore Biosurgery 5/1/03- 4/30/04 $126,614Lipo-Derived Stem Cells for Myocardial InfarctionThe goal of this project is to determine if lipo-derived stem cell improve left ventricular function following myocardial infarction.Role: Principal investigator

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14. Guidant Inc. 2/1/03-1/31/04 $20,000DELIVER Clinical TrialThe goal of this study is demonstrate of the effect of a paclitaxel coated stent in prevention of restenosisRole: Principal Investigator

15. Guidant Inc, 1/6/04 to 31/05/05 FUTURE 4 Clinical TrialThe goal of this multicenter clinical trial is to compare the efficacy of the Everolimus Champion Stent (Guidant Inc) versus Paclitaxel eluting TAXUS stent.Role: Co-Investigator

16. Cordis 6/1/04-5/31/05 $9,770CYPHERTM Sirolimus-Eluting Coronary Stent – STELLAR Registry Clinical TrialRole: Principal Investigator

17. Pfizer/Parke-Davis 9/1/99-8/31/03 $84,875A Prospective, Randomized, Double-Blind Study Comparing the Effects of Atorvastatin vs. Pravastatin on the Progression and Quantification of Coronary Artherosclerotic Lesions as Measured by IVUS - REVERSAL Clinical TrialThis is a clinical trial which compares the effectiveness of two lipid lowering drugs on the progression and quantification of coronary artherosclerotic lesions.

18. AHA-WSA 0120115Y 7/1/01-6/30/02 $45,000Bone Marrow Induced Cardiac Angiogenesis to Support Cell TransplantationThe aim of this project is to develop novel therapeutic agents derived from bone marrow in order to promote cardiac angiogenesis.Role: MENTOR

19. Radiant Medical Inc. 7/1/02-6/30/04 $8,891 COOL MI Clinical TrialRole: Co-investigator

20. Boston Scientific, Inc. 4/1/02-3/31/05 $29,425 SYMBIOT III: A Prospective Randomized Trial Evaluation of the SYMBIOT III Covered Stent System in Saphenous Vein Grafts – SYMBIOT III Clinical TrialThis is a clinical trial to assess the safety and efficacy of a coated stent to inhibit restenosis when implanted in saphenous vein grafts.Role: Principal Investigator

21. THEROX Inc. 10/1/02-9/30/03 $26,023HOT MI Clinical TrialRole: Principal investigator

22. Abbott Laboratories 10/1/01-6/30/03 $8,000

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A Phase IIIb Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety, Efficacy and Tolerability of Fenoldopam Mesylate in Subjects Undergoing Invasive Cardiology ProceduresThis is a clinical trial which assesses the safety and efficacy of the use of fenoldopam mesylate in patients undergoing invasive cardiac procedures.Role: Principal Investigator

23. Sankyo Inc. 7/1/03-6/30/04 $15,3000 ACTIVATE Clinical TrialRole: Principal investigator

24. REVITALIZE pilot study 2005 $250,000 (private donor)Studying the effects of intracoronary administration of autologous bone marrow transplantation in acute myocardial infarction and primary angioplasty. Role: Principal investigator

25. Cordis Corporation 8/1/03-6/30/05 $15,091Evaluation of the Steeplechaser StentThe goal of this study is to evaluate user characteristics of drug coated stent and the stent delivery system.Role: Principal Investigator

26. Edwards Lifesciences 10/1/02-9/30/05 $43,373Percutaneous Interventions of Aortic and Mitral ValveThe goal of this study is to test and develop three devices that can be used to repair the mitral and aortic valves percutaneously.Role: Principal Investigator

27. Edwards Lifesciences 7/1/04-6/30/05 $63,134Percutaneous Interventions of Aortic and Mitral ValveThe goal of this study is to test and develop a device that can be used to repair the mitral valve percutaneously in an ischemic animal model.Role: Principal Investigator

28. Amgen, Inc.12/1/02-11/30/04 $53,310G-CSF for Acute Myocardial InfarctionThe purpose of this study is to assess the ability of G-CSF to stimulate and mobilize native stem cells to translocate into the site of a myocardial infarct in order to improve left ventricular function after a heart attack.Role: Principal Investigator

29. Private Donor 6/1/01-5/31/03 $31,000The Angiogenic Efficacy of Bone Marrow Transplantation in an Experimental Model of MI

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The goal of this study is determine whether or not transplantation of bone marrow to the heart can induce angiogenesis and reduce the amount of tissue damaged by myocardial infarction.Role: Principal Investigator

30. Lincy Foundation 4/07 – 3/10 $4,000,000Randomized Evaluation of Intracoronary Transplantation of Bone Marrow Stem Cells in Myocardial Infarction (REVITALIZE) pilot.Role: Principal Investigator

31. Donald W. Reynolds Cardiovascular Clinical Research Center”7/1/2003-6/30/2007The Johns Hopkins Reynolds Center is a broad, multidisciplinary approach to the problem of sudden cardiac death (SCD) associated with atherosclerosis. Role: Co-Project Leader

32. Cellular Cardiomyoplasty for Acute and Chronic Ischemia” 9/1/2005-8/31/2010Principal Investigator: Eduardo Marbán, M.D., Ph.D.Agency: NIH, NHLBIType: U54 HL081028-01 The major goal of this Specialized Center for Cell Therapeutics proposal aims to develop cellular cardiomyoplasty for the treatment of ischemic heart disease, both post-myocardial infarction left ventricular dysfunction as well as chronic ischemic cardiomyopathy.Role: Co-Project Leader

33. Private Donor 7/05-Current $400,000Randomized Evaluation of Intracoronary Transplantation of Bone Marrow Stem Cells in Myocardial Infarction (REVITALIZE) pilot.Role: Principal Investigator

34. Lincy Foundation 4/07 – 3/10 $4,000,000Randomized Evaluation of Intracoronary Transplantation of Bone Marrow Stem Cells in Myocardial Infarction (REVITALIZE) pilot.Role: Principal Investigator

35. Internally funded study 7/1/05-6/30/11 0.12 calendarPI: Raj Makkar, MD $100,000 1% effortREVITALIZE Clinical Trial (Phase I): Randomized Evaluation of Intracoronary Transplantation of Bone Marrow Stem CellsThe goal of this study is to evaluate the ability of autologous bone marrow stem cells to promote myocardial regeneration and stimulation of neovascularization when transplanted into patients after myocardial infarction.

36. Lincy Foundation 4/1/07-3/30/12 .009 calendarPI: Raj Makkar, MD $1,000,000 Less than 1%

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REVITALIZE Clinical Trial (Phase II): Randomized Evaluation of Intracoronary Transplantation of Bone Marrow StemCellsThe goal of this study is to evaluate the ability of autologous bone marrow stem cells to promote myocardial regeneration and stimulation of neovascularization when transplanted into patients after myocardial infarction.

37. Donald W. Reynolds Foundation 7/1/2003-6/30/11 2.4 calendarCardiovascular Clinical Research Center”(PI Marbán) $2,173,795 20% effortRole: Project 3 Leader & Animal Core LeaderThe Johns Hopkins Reynolds Center is a broad, multidisciplinary approach to the problem of sudden cardiac death (SCD) associated with atherosclerosis.

38. Agency: NIH, NHLBI (PI Marbán) 9/1/05-8/31/11 3 calendarRole: Co-Project Leader .$2,523,072 25% effortCellular Cardiomyoplasty for Acute and Chronic Ischemia”Type: U54 HL081028-01 (Project 3 & Animal Core)The major goal of this Specialized Center for Cell Therapeutics proposal aims to develop cellular cardiomyoplasty for the treatment of ischemic heart disease, both post-myocardial infarction left ventricular dysfunction as well as chronic ischemic cardiomyopathy.

39. Lincy Foundation 8/1/07-7/31/11 0.12 calendarPI: Raj Makkar, MD $260,000 1% effortMakkar Cardiac Stem Cell ProjectsThe goal of these projects is to study the use of cellular therapy to assist with repair of myocardial injury.

40. Edwards Lifesciences, Inc. 1/1/08–12/31/13 0.24 calendarPI: Raj Makkar, MD $60,000 2% effortTranscatheter Aortic Valve Replacement in Aortic Stenosis Patients (PARTNER Trial)The goal of this trial is to evaluate a transcatheter system for aortic valve replacement.

41. Lincy Foundation 12/1/2008-11/30/2011 <.12 calendarPI: Raj Makkar, MD $352,707 .1%Effect of NOGA Catheter-Guided Intramyocardial Autologous Cardiac Stem Cell Delivery on Left Ventricular Remodeling after Infarction The goal of this project is to evaluate the effect of delivery of cardiac stem cells via the NOGA catheter guided system on left ventricular remodeling after infarction.

42. Lincy Foundation 3/1/2009- 2/28/2012 <.12 calendarPI: Raj Makkar, MD $51,020 .1%The Effects of Cardiac Stem Cell Delivery on Left Ventricular Remodeling after InfarctionThe goal of this project is determine the effect of cardiac stem cell delivery via open sternum on left ventricular remodeling after infarction.

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43. Lincy Foundation 7/1/2007-6/20/2011 <.12 calendarPI: Raj Makkar, MD $69,081 .1%CVIC Research Fellowship FundThis project provides support for research fellows who conduct the stem cell studies.

44. NIH/NHLBI ARRA-1RCHL103556 Capricor, Inc. 5/17/10-4/30/2013PI: Eduardo Marban, MD $106,418 10% effortSafety and Efficacy of Autologous Cardiosphere-derived Stem Cells in Advanced Heart FailureThe goals of this project are to develop cGMP-compliant cell manufacturing procedures, to file an IND and obtain FDA approval to conduct two clinical trials, and to conduct both a phase 1 and a phase 2 clinical trial examining the safety and efficacy of autologous cells given via direct injection as an adjunct to ventricular assist device placement. Role: Co-Investigator

45. NIH/NHLBI ARRA-1RCHL103556 Capricor, Inc. 8/01/12-4/30/2013PI: Raj Makkar, M.D. $255,964 1% effortAllogeneic Heart Stem Cells To Achieve Myocardial Regeneration: ALLSTAR Study

46. ALLSTAR (ALLogeneic Heart Stem) – 11/14/2012 – 3/31/2017 $417,154.73CapricorRole: Principal Investigator

47. GRF – Lincy Foundation – 5/10/2007 – 6/30/2020 $4,000,000CSRI (General Research Fund – Internal Funding)Role: Principal Investigator

48. Transcutaneous Aortic Valve Implant – 10/1/07 – 12/1/2017 $3,177,850.00Edwards LifesciencesRole: Principal Investigator

49. Cardiac Stem Cell Projects – Sma – 10/1/2012 – 9/30/2017 $244,436.00CSRI (General Research Fund – Internal Funding)Role: Principal Investigator

50. GRF – Rajendra Makkar – 6/1/2013 – 6/30/2020CSRI (General Research Fund – Internal Funding)Role: Principal Investigator

51. Assessment of SAVR & TAVR Valv – 12/1/2014 – 11/30/2016 $124,862.00CSRI (General Research Fund – Internal Funding)Role: Principal Investigator

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52. Partner II Trial Sapien XT Val – 3/15/2011 – 2/28/2017 $8,927,149.00Edwards LifesciencesRole: Principal Investigator

53. Transcutaneous Aortic Valve Im – 10/1/2007 – 12/1/2017Edwards LifesciencesRole: Principal Investigator

54. Transcatheter Aortic Valve Pro – 9/15/2010 – 9/14/2020 $1,658,776.00St. Jude Medical, Inc.Role: Principal Investigator

55. EXCEL Clinical Trial – 4/22/2013 – 3/31/2017 $7,912.00Abbott VascularRole: Principal Investigator

56. SURTAVI – 12/11/2013 – 12/10/2016 $1,042,994.00Medtronic, Inc.Role: Principal Investigator

57. RECOVER RIGHT – 1/8/2014 – 1/7/2017 $11,750.00ABIOMEDRole: Principal Investigator

58. Aortic Valve Implantation – 4/10/2014 - 4/9/2017 $915,105.40St. Jude Medical, Inc.Role: Principal Investigator

59. PORTICO Re-Sheathable Tra – 6/9/2014 – 6/8/2017 $613,250.00St. Jude Medical, Inc.Role: Principal Investigator

60. DYNAMIC – 7/1/2014 – 9/30/2015 CapricorRole: Principal Investigator

61. SENTINEL STUDY – 1/2/2015 – 1/1/2018 $469,057.00Claret Medical, Inc.Role: Principal Investigator

62. Claret Procedure – 1/7/2015 – 1/6/2018 $686,000.00Claret Medical, Inc.Role: Principal Investigator

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63. Tiara Neovasc – 1/23/2015 – 1/22/2018 $11,750.00Neovasc Medical Inc.Role: Principal Investigator

64. IP 011 – SALUS: The Direct Flow – 1/23/2015 – 1/22/2018 $11,750.00Direct Flow Medical, Inc.Role: Principal Investigator

65. REPRISE III Study – 3/12/2015 – 3/11/2018 $869,189.48Boston Scientific CorpRole: Principal Investigator

66. 2014-04: Early Feasibility Study – 2/8/16 – 2/7/2019 $11,750.00Edwards LifesciencesRole: Principal Investigator

67. PARTNER 3 Trial/2015-08-A Pros – 8/10/2016 – 8/9/2019 $11,750.00Edwards LifesciencesRole: Principal Investigator

68. REFLECT TRIAL – The Randomization – 2/16/2016 – 2/15/2019 $11,750.00Keystone Heart Ltd.Role: Principal Investigator

Lectures and Presentations:

1. “Revamping Our Approach to Acute Coronary Syndromes: A New Comprehensive Perspective on Pathophysiology, Diagnosis and Treatment” Pasadena, CA July 15, 1998

2. Tarzana Regional Medical Center “ReoPro: Summary of Clinical Trials” Tarzana, CA August 6, 1998

3. “Acute Coronary Syndromes: Emerging Management Strategies” Irving, TX July 8-9, 1998

4. Discovery International “Clopidogrel Speakers Training Consultants Program” Los Angeles, CA September 18-19, 1998

5. Benson Hotel “Acute Coronary Syndromes: A Revolution in Practice” Portland, OR September 22, 1998

6. 2nd International Congress on Coronary Artery Disease – From Prevention to Intervention Florence, Italy October 18-21, 1998

7. St. John’s Hospital “ReoPro (abciximab) Summary of Clinical Trials” Oxnard, CA October 29, 1998

8. Bakersfield Memorial Hospital “Acute Coronary Syndromes: Emerging Management Strategies” November 18, 1998

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9. Hilton Hotel“ Adjunctive Pharmacology in Acute Coronary Syndromes, Coronary Interventions, and Acute Myocardial Infarction” San Bernardino, CA November 19, 1998

10. St. John’s Hospital “Platelet Glycoprotien IIb/IIIa Receptor Inhibitor Therapy” January 29, 1999

11. Grand Hyatt San Francisco “The 2b/3a Frontier: Applications in Clinical Practice” San Francisco, CA February 11, 1999

12. Scripps Memorial Hospital Grand Rounds La Jolla, CA April 13, 199913. Hotel Nikko, Beverly Hills “Evolving Treatment of Acute Coronary Syndromes:

New Agents and Applications” May 4, 199914. Hyatt Regency Monterey SCAI Annual Meeting “Liquid Filled Balloons &

RADIANT Trial” Monterey, CA May 15, 199915. “Acute Coronary Syndromes: A New Treatment Strategy for the New Millennium”

The Beverly Hills Hotel Beverly Hills, CA 90210 June 5, 199916. “Taiwan Society of Cardiology Intervention Symposium and Live Case

Demonstration Course” Taipei, Taiwan June 12-13, 199917. “Antiplatelet Strategies in Atherosclerotic Heart Disease” Utah Valley Medical

Center, Provo, Utah August 23, 199918. “Novel Anti-Platelet Strategies” St. Bernadine Medical Center, San Bernardino, CA

August 26, 199919. “14th Annual Cardiology Symposium” Glendale Adventist Medical Center

September 30, 199920. “International Conference on Transcatheter Cardiovascular Interventions” New

Delhi, India January 27-29, 200021. Preceptorship Program Cedars-Sinai Medical Center Los Angeles, CA February 24-

25, 200022. Loma Linda Hospital Grand Rounds “Thrombotic Complications and

Cardiovascular Disease” April 27, 200023. Long Beach VA Medical Center Grand Rounds “Cardiovascular Disease: Advances

in Treatment and Prevention – the Role of Antiplatelet Agents” May 12, 200024. Kaiser Permanente, West Los Angeles Grand Rounds “Acute Coronary Syndromes”

June 6, 200025. International Society of Heart Failure, Inc. 7th World Congress on Heart Failure –

Mechanisms and Management Co-Chair of Session Vancouver, BC, Canada July 9-12, 2000

26. Eisenhower Medical “Advances in Antiplatelet Therapy in the Treatment of Atherosclerotic Vascular Disease” Palm Springs September 28, 2000

27. TCT 2000 Washington, DC October 17-22, 200028. American College of Cardiology Angelo May Guest Lectureship Orlando, FL

October 30, 200029. AHA Meetings Co-Chair of Session New Orleans, LA November 12-14, 200030. Preceptorship Program Cedars-Sinai Medical Center Los Angeles, CA March 29-

30, 200131. Grand Rounds Loma Linda University Loma Linda, CA June 14, 200132. St. John’s Regional Medical Center “Current Management of Acute Coronary

Syndrome” Joplin, Missouri June 18, 2001

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33. Freeman Health System “Current Management of Acute Coronary Syndrome” Joplin, Missouri June 18, 2001

34. Cox Medical Center South “Current Management of Acute Coronary Syndrome” Springfield, Missouri June 19, 2001

35. Ritz Carlton “Oral Antiplatelet Strategies in Coronary Artery Disease” Rancho Mirage, CA August 22, 2001

36. The Lodge at Koele “Vascular Brachytherapy and Local Drug Delivery” Lanai City, Hawaii August 24-26, 2001

37. Ground Rounds Garfield Hospital Monterrey Park, CA September 27, 200138. Portland Providence Medical Center “Current Management of Acute Coronary

Syndromes” Portland, Oregon October 2, 200139. Las Vegas VA Medical Center “Current Management of Acute Coronary

Syndromes” Las Vegas, Nevada October 10, 200140. Grand Rounds Harbor-UCLA Medical Center “Current Management of Acute

Coronary Syndromes” Torrance, CA October 15, 200141. Preceptorship Program Cedars-Sinai Medical Center Los Angeles, CA April 4-5,

200242. Grand Rounds Encino/Tarzana Medical Center "Oral Anti-Platelet Strategies in

Acute Coronary" Tarzana, CA June 6, 200243. Invited Speaker 8th World Congress on Heart Failure Washington, DC July 14, 200244. Scripps Center of Excellence Lecture Symposium “Platelet 2b/3a Inhibitors:

Unsettled issues-diabetics, who is to treat, impact of CPK elevations and more” San Diego, CA January 24, 2003

45. The 18th Annual Cardiovascular Conference in Hawaii “Coronary intervention in patient with diabetes: Selective benefit of platelet glycoprotein Iib/IIIa receptor inhibitors and mechanisms of risk reduction” Kona, Hawaii February 17-21, 2003

46. Best Meeting (Board of External Specialists in Thrombosis) Chair Session Paris, France March 18, 2003

47. Atherothrombosis Risk Management: Impact of Long-term Antithrombotic Therapy “Key Trials in the Development of the New ACS Guidelines” Long Beach, CA April 3, 2003

48. The Second Annual California-Nevada Cardiovascular Symposium “Interventional Cardiology in 2003” Las Vegas, NV May 3, 2003

49. St. Mary Medical Center “Advances in Endovascular Intervention” Apple Valley, CA July 25, 2003

50. 15th Annual Scientific Symposium TCT 2003 Moderator Washington, DC September 15-19, 2003

51. Fairmont Hotel “Controversies in Adult Cardiac Surgery” Santa Monica, CA October 2, 2003

52. Grand Rounds Lakewood Regional Medical Center “Integrating Lipid Therapy into ACS Critical Pathways” Lakewood, CA October 3, 2003

53. Third Annual Cardiovascular Nursing Symposium Park Plaza Hotel Convention Center “Drug Eluting Stents” November 1, 2003

54. 55th Annual Meeting in Cardiology Society of India Kolkatta, India Keynote Speaker: Stem Cell Therapy in Myocardial Repair December 3-7, 2003

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55. 55th Annual Meeting in Cardiology Society of India Kolkatta, India Keynote Speaker: Angiogenesis: Will it Work? December 3-7, 2003

56. 55th Annual Meeting in Cardiology Society of India Kolkatta, India Keynote Speaker: Percutaneous Mitral Valve Repair: Dawn of a New Era? December 3-7, 2003

57. Harbor-UCLA Medical Center “Stem Cell Therapy for Myocardial Repair” Torrance, CA January 12, 2004

58. USC, Keck School of Medicine “Stem Cell Therapy for Myocardial Repair” Los Angeles, CA January 13, 2004

59. TCT 2004 Meeting, Washington DC, Invited Faculty60. International Summit of Coronary Artery Disease, Dubai,Feb 2005, Invited Faculty61. Judge for Young Investigators Award Competition. 2005 American College of

Cardiology Scientific Sessions Orlando, FL62. Wayne State University symposium, Detroit MI, April 2005, Invited Faculty63. TCT Asia 2005, Seoul, Korea, Invited Faculty64. Invited Faculty, American College of Cardiology Annual Meeting, 200665. Invited Faculty, I2 Summit at American College of Cardiology, 200666. Invited Faculty, Transcatheter Therapeutics, 200667. Invited Faculty, 2nd Asia International Cardiology Therapeutics, New Delhi.

Demonstrated live cases to over 1500 interventionalists.68. Invited Faculty, Annual C3 Cardiovascular Conference, India, 200669. Grand Rounds City of Hope National Medical Center “Reperfusion Strategies in

Patients with STEMI”, Duarte, CA November 7, 200670. Invited Faculty, American College of Cardiology I2 Summit 200771. Invited Faculty TCT 2007, Washington DC72. Grand Rounds at Victor Valley Community Hospital “Management of Patinets with STEMI: Applying the ACC / AHA Guidelines”, Victorville, California, January 31, 2007.73. Invited Faculty, Critical Challenges in Cardiovascular Medicine – Advancing Management of Acute Coronary Syndromes (ACS): Establishing Emergency Department and Interventional Cardiology Therapeutic Teams (EDICT) to Optimize Patient Care, Los Angeles, California, June 23, 2007.74. Invited Faculty, SIS 2007, Seattle, WA, August 1-4, 2007.75. Grand Rounds Torrance Memorial Medical Center “Complex Lesion – The Growing Challenge in PCI”, Torrance, California, August 20, 2007.

76. Grand Rounds at Maui Memorial Medical Center “The Evolving Algorithm Concerning Higher Risk PCI”, Wailuku, HI, September 14, 2007. 77. Program Director, “Controversies and Advances in the Treatment of Cardiovascular Disease”, Beverly Hills, CA, October 4-5, 2007. 78. Grand Rounds, Saint Helena Hospital “Targeting Atherothrombosis: A Common Denominator in ACS, PAD and Stroke”, St. Helena, CA, October 11, 2007. 79. Invited Faculty TCT 2007, Washington DC, October 20-25, 2007. 80. Moderator, AHA Meetings, Orlando, FL, November 5-7, 2007. 81. Grand Rounds, Sharp Chula Vista Medical Center “Pre-Hospital and Emergency Department Management of STEMI”, Chula Vista, CA, November 13, 2007.

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82. Invited speaker, “Inaugural Cabo Interventional Summit. A Meeting of the Americas”, Cabo San Lucas, March 17-21, 2008. 83. Invited Faculty, The SCAI Annual Scientific Sessions, Chicago, IL, March 29-April 1, 2008. 84. Invited Speaker, Angioplasty Summit 2008-TCT Asia Pacific, Seoul, Korea, April 21-25, 2008. 85. Invited Speaker, “Heart and Vascular Symposium”, Fresno, CA, May 3, 2008. 86. Invited Speaker, “5th Annual 2008 Oregon ACC Cardiovascular Symposium”, Portland, Oregon, May 17, 2008. 87. Program Director, “Controversies and Advances in the Treatment of Cardiovascular Disease”, Beverly Hills, CA, September 4-5, 2008. 88. Grand Rounds, University of California, Irvine “Percutaneous Aortic Valve Replacements”, Irvine, California, September 22, 2008. 89. Invited Faculty, TCT 2008, Washington, DC, October 12-17, 2008. 90. Proctor, PARTNER TRIAL, Stanford Medical Center, December 16, 2008. 91. International Guest Faculty, 5th International Transradial Intervention Course Coronary and Peripheral, Gujarat, India, January 3-4, 2009. 92. Proctor, PARTNER TRIAL, Scripps Clinic, La Jolla, California, January 7, 2009 93. Invited Faculty, 2nd Annual Cabo Interventional Summit, Cabo San Lucas, March 16- 20, 2009. 94. Invited Faculty, i2 Summit 2009, American College of Cardiology, Orlando, Florida, March 29-31, 2009. 95. Proctor, PARTNER TRIAL, Scripps Clinic, La Jolla, California, March 31, 2009. 96. Invited Faculty, 3rd Annual Cardiovascular Symposium, Los Robles Hospital & Medical Center, Thousand Oaks, CA, April 18, 2009. 97. Invited Faculty, Dallas-Leipzig International Valve Congress 2009, Dallas, Texas, April 23-25, 2009. 98. Invited Speaker, SCAI 32nd Annual Scientific Sessions, Las Vegas, NV, May 6-9, 2009. 99. Proctor, PARTNER TRIAL, Intermountain Medical Center, Salt Lake City, Utah, May 15, 2009. 100. Invited Speaker, 09 ISMICS, Westin St. Francis Hotel, San Francisco, CA , June 3-6, 2009. 101. Invited Faculty, C3 Capital Cardiovascular Conference, Baltimore, Maryland, June 14-17, 2009. 102. Faculty, 3rd Annual Tips and Tricks in Complex Interventional Cardiovascular Therapy, Napa Valley, California, July 31-August 1, 2009. 103. Invited Speaker, CME Program, Torrance Memorial Medical Center, August 19, 2009. 104. Invited Faculty, TCT 2009, San Francisco, CA, September 21-25, 2009. 105. Program Director, “Controversies and Advances in the Treatment of Cardiovascular Disease”, Beverly Hills, CA, October 1-2, 2009. 106. Invited Faculty, 2nd Annual Cardiovascular Symposium, Torrance, CA, October 9, 2009. 107. Proctor, PARTNER TRIAL, Cornell University Medical Center, New York, December 16, 2009.

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108. Invited Faculty, ISMICS 2009 Winter Workshop, The MedCity, Delhi, India. December 8-15, 2009. 109. Invited Speaker, Grand Rounds, University of California, San Francisco, February 17, 2010. 110. Invited Faculty, 2nd Annual PanVascular Summit, Midway, Utah, February 19, 2010. 111. Invited Faculty, India Live 2010, Live Case Demonstration from Indian Site Ahmedabad, February 26, 2010. 112. Invited Speaker, Grand Rounds, Banner Good Samaritan Medical Center, Arizona, March 2, 2010. 113. Panelist, Case Presenter, Poster Discussant, ACC.10, Georgia, Atlanta, March 14-16. 114.Guest Speaker, 9th Annual Cardiology in Primary Care Conference, Antelope Valley Hospital, Lancaster, CA, March 27, 2010. 115. Guest Speaker, AATS 90th Annual Meeting, Toronto, Ontario, Canada, May 1-5, 2010. 116.Guest Speaker, SCAI 33rd Annual Scientific Sessions, San Diego, CA, May 5-8, 2010. 117. Guest Speaker, Los Robles Hospital and Medical Center, Thousand Oaks, CA, May 15, 2010. 118. Invited faculty, Highlights in Cardiovascular Therapies – A Contemporary Course for Cardiac and Vascular Specialists, Seattle, Washington, May 21, 2010. 119. Invited Faculty, TVT 2010: Roadmap to Achieving Optimal Success, Seattle, Washington, June 6-9, 2010. 120. Co-chair, The First Cedars-Sinai Regenerative Medicine Scientific Symposium, Cedars-Sinai Medical Center, Los Angeles, CA, June 14, 2010. 121. Invited Faculty, 2010 Live Symposium of Complex Coronary & Vascular Cases, Mount Sinai Medical Center, New York, NY, June 16-19, 2010.122. Invited Faculty, C3 Complex Cardiovascular Catheter Therapeutics Advanced Endovascular and Coronary Intervention Global Summit, Baltimore Marriott Waterfront, Baltimore, Maryland, June 20-24, 2010123. Invited Faculty, Hawaii 2010 – Principles and Perspectives in Interventional Cardiology – State of the Art, Mauna Kea Beach Hotel & Hapuna Beach Prince Hotel, Kohala Coast, Hawaii, July 19-23, 2010.124. Invited Faculty, Tips & Tricks in Complex Interventional Cardiovascular Therapy - CICT, San Francisco, CA, July 30-31, 2010.125. Invited Speaker, Grand Rounds, Long Beach Memorial Hospital, Long Beach, CA, September 15, 2010.126. Invited Faculty, TCT 2010, Washington DC, September 21-25, 2010.127. Program Director, Controversies and Advances in the Treatment of Cardiovascular Disease, The Tenth in the Series, Beverly Hills, CA, October 7-8, 2010.128. Invited Speaker, Cardiology & Electrophysiology 2010: Concepts and Controversies, Hyatt Regency Sacramento, CA, October 23, 2010.129. Invited Speaker, Cardiology Grand Rounds, Transcatheter Aortic Valve Implantation: Progress Report. Long Beach Memorial Hospital, November 3, 2010.130. Invited Speaker, 4th Acute Myocardial Infarction (AMI) Course & Complex Coronary Intervention Workshop, New Delhi, India, November 12-14, 2010.

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131. Invited Speaker/Moderator, STS Transcatheter Valve Therapies Symposium, Chicago, IL, December 3-4, 2010.132. Invited Faculty, 2010 Dallas-Leipzig International Valve Conference, Dallas, Texas, December 8-11, 2010.133. Invited Faculty, Conference on Cell Therapy for Cardiovascular Disease, New York, NY, January 20-21, 2011.134. Invited Faculty, Heart Failure 2011 – An Update on Therapy, Los Angeles, California, January 29, 2011.135. Invited Faculty, Endovascular Summit, Newport Beach, California, February 5, 2011.136. Invited Faculty, 8th Annual Chronic Total Occlusion Summit and Left Main Coronary Interventions Course, New York, NY, February 14-16, 2011.137. Invited Faculty, 2011 Scottsdale Interventional Forum, Scottsdale, Arizona, February 17-19, 2011.138. Invited Faculty, Interventional Cardiology 2011, 26th Annual International Symposium, Snowmass, Colorado, March 13-18, 2011.139. Invited Speaker, The Los Angeles Society of Echocardiography, Los Angeles, California, April 16, 2011.140. Invited Faculty, Angioplasty Summit-TCTAP 2011, Seoul, Korea, April 27-29, 2011.141. Invited Faculty, Second Annual Highlights in Cardiovascular Therapies: A contemporary course for cardiac & vascular specialists, Seattle, Washington, May 20, 2011.142. Invited Faculty, SCAI 2011 Scientific Sessions, Baltimore, Maryland, May 4-7, 2011.143. Invited Faculty, Transcatheter Valve Therapies: An Advanced Scientific and Clinical Workshop, Vancouver, Canada, June 5-7, 2011.144. Invited Faculty, PICS-AICS 2011, Boston, Massachusetts, July 24-27, 2011.145. Invited Faculty, Tips & Tricks in Complex Interventional Cardiovascular therapy (CICT), San Francisco, CA, July 29-30, 2011.146. Invited Speaker, Cedars-Sinai Medical Center Grand Rounds: CABG vs Stenting for Left Main Disease, August 23, 2011.147. Invited Speaker, West Los Angeles Healthcare Center’s Department of Medicine Grand Rounds: Transcatheter Aortic Valve Replacement: An Update, September 21, 2011.148. Program Director, Controversies and Advances in the Treatment of Cardiovascular Disease, The Eleventh in the Series, Beverly Hills, CA, October 13-14, 2011.149. Invited Faculty, 18th Kamakura Live Demonstration Course, December 8-12, 2011.150. Invited Faculty, Cell Therapy 2012, Columbia University, New York, New York, January 25-27, 2012.151. Invited Faculty, Complex PCI: Left Main and CTO Summit, New York, New York, February 23-25, 2012.152. Invited Faculty, India Live-2012. New Delhi, India. February 24-26, 2012.153. Invited Faculty, 4th Annual Scientific Meeting – Heart Valve Society of America/Society of Heart Valve Disease, New York, New York, April 12-14, 2012.154. Invited Faculty, PICS-AICS 2012, Chicago, Illinois, April 15-18, 2012.

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155. Invited Faculty, 6th Annual Women and Ischemic Heart Disease Symposium, Los Angeles, CA, April 27, 2012.156. Invited Faculty, Los Robles Cardiovascular Symposium, Los Robles, California, April 28, 2012.157. Invited Faculty, SCAI 2012, Las Vegas, Nevada, May 9-12, 2012.158. Invited Faculty, Transcatheter Valve Therapies: An Advanced Scientific and Clinical Workshop. Seattle, Washington, June 2-5, 2012.159. Invited Faculty, 2012 Live Symposium of Complex & Vascular Cases, New York, New York, June 14-15, 2012.160. Invited Speaker, AAPI Convention, Long Beach, California, June 28, 2012.161. Invited Faculty, CICT 2012, San Francisco, California, July 27-28, 2012.162. Invited Faculty, Fortis Heart Conclave, New Delhi, India, September 2, 2012.163. Program Director, Controversies and Advances in the Treatment of Cardiovascular Disease, The Twelfth in the Series, Beverly Hills, CA, September 21-22, 2012.164. Invited Faculty, PCR London Valves 2012, London, United Kingdom, September 30-October 2, 2012.165. Invited Faculty, 8th AICT 2012, Delhi NCR, India, October 6, 2012.166. Invited Faculty, VIVA, Las Vegas, Nevada, October 8-9, 2012.167. Invited Faculty, TCT 2012, Miami, Florida, October 22-26, 2012.168. Invited Faculty, Vanderbilt Valve Symposium, Nashville, TN, October 29-30, 2012.169. Invited Faculty, AHA Meetings 2012, Los Angeles, California, November 3-7, 2012.170. Invited Faculty, 3rd Annual State of the Art Cardiovascular Medicine Conference, San Diego, California, November 30-December 2, 2012.171. Invited Faculty, Dallas-Leipzig Valve, Dallas, Texas, December 5-7, 2012.172. Invited Faculty, CTO-LM Summit 2013, New York, New York, February 21-23, 2013.173. Invited Faculty, India Live 2013, Chennai, India, February 27-March 2, 2013.174. Invited Faculty, The 77th Annual Scientific Meeting of the Japanese Circulation Society, Yokohama, Japan, March 15-17, 2013.175. Invited Speaker, ACC Oklahoma Chapter Annual Meeting, April 6, 2013.176. Invited Faculty, 18th Angioplasty Summit-TCTAP 2013, Seoul, Korea, April 23-26, 2013.177. Invited Faculty, 2013 Live Symposium of Complex Coronary & Cardiovascular Cases, New York, New York, June 13-14, 2013.178. Invited Faculty, 2013 CICT Conference, San Francisco, California, August 2-3, 2013.179. Invited Faculty, 24th Annual Cardiovascular Interventions, La Jolla, California, October 1-4, 2013.180. Program Director, Controversies and Advances in the Treatment of Cardiovascular Disease, The Thirteenth in the Series, Beverly Hills, CA, November 21-22, 2013.181. Invited Faculty, CIMSRE-Con 2014, Ahmedabad, India, January 10-12, 2014.182. Invited Faculty IC3D-Cell Therapy 2014, New York, NY, January 22-24, 2014.183. Invited Faculty, CRT 2014, Washington DC, February 23-25, 2014.184. Invited Faculty, India Live 2014 “Revolutionizing Interventional Cardiology in the Region”, Taj Palace, New Delhi, India, February 28 – March 2, 2014.

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185. Invited Faculty, “Championing Care for the Patient with Aortic Stenosis: Optimize your TAVR Center”, American College of Cardiology’s 63rd Annual Scientific Session, ACC.14, Washington, DC. March 29, 2014.186. Moderator, SCAI 2014, Las Vegas, NV, May 29, 2014.187. Invited Faculty, 4th Lugano Stem Cell Meeting, Lugano, Italy, June 23-24, 2014.188. Invited Faculty, The 23rd Annual Meeting of the Japanese Association of Cardiovascular Intervention and Therapeutics, Nagoya, Japan, July 24-26, 2014.189. Invited Faculty, PCR London Valves 2014, London, England, September 28-30, 2014.190. Invited Faculty, TCT 2014, Washington, D.C., September 13-17, 2014.191. Invited Keynote Speaker, Case-Based Coronary & Structural Heart Intervention Update Chicago (CSI) 2014, Chicago, IL, November 1, 2014.192. Invited Faculty, 1st Annual Cardiovascular Symposium, Bakersfield, CA, November 8, 2014.193. Invited Faculty, American Heart Association, Chicago, IL, November 17, 2014.194. Invited Faculty, SCIA 2014 Fall Fellows Course, Las Vegas, NV, December 9, 2014.195. Invited Faculty, DLV 2014, Dallas, TX, December 10-11, 2014.196. Invited Faculty, India Live 2015, Chennai, India, February 24-28, 2015.197. Invited Faculty, CRT2015, Washington DC, February 21-24, 2015.198. Invited Faculty, Snowmass 2015, Snowmass, Colorado, March 1-6, 2015.199. Invited Speaker, Grand Rounds at University of California, Irvine, Irvine, California, April 8, 2015.200. Invited Faculty, 20th Cardiovascular Summit-TCTAP 2015, Seoul, Korea, April 28- May 1, 2015.201. Invited Faculty, 2015 SCAI Scientific Session, San Diego, CA, May 6-9, 2015.202. Invited Faculty, EuroPCR, Paris, France, May 18-23, 2015.203. Invited Faculty, TVT Chicago, Chicago, Illinois, June 4-6, 2015.204. Invited Faculty, SDCI 2015 (San Diego Cardiovascular Interventions), San Diego, CA, July 11, 2015.205. Invited Faculty, CICT 2015, San Francisco, CA, July 31-August 1, 2015.206. Invited Faculty, PCR London Valves, Berlin, Germany, September 20-22, 2015.207. Invited Faculty, TCT 2015, San Francisco, CA, October 11-15, 2015.208. Invited Faculty, 2nd Annual Cardiovascular Symposium, Bakersfield, CA, November 14, 2015.209. Invited Faculty, Heart Failure University, Los Angeles, CA, December 11-13, 2015.210. Invited Faculty, 22nd Kamakura Live Demonstration Course 2015, December 18-20, 2015, Yokohama, Japan.211. Invited Faculty, CRT 2016, Washington, DC, February 20-23, 2016.212. Invited Faculty, Interventional Cardiology 2016: 31st Annual International Symposium, March 6-11, 2016, Snowmass, Colorado.213. Invited Faculty, ACC 16, April 2-4, 2016, Chicago, Illinois.214. Invited Faculty, 21st CardioVascular Summit-TCTAP 2016, April 26-29, 2016, Seoul, Korea.215. Invited Faculty, SCAI 2016, May 4-7, 2016, Orlando, Florida.216. Invited Faculty, EuroPCR 2016, May 17-20, 2016, Paris, France.

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217. Invited Faculty, Ventura CVD Symposium, June 4, 2016, Ventura, California.218. Invited Faculty, World Congress of Cardiology, June 4-7, 2016, Mexico City, Mexico.219. Invited Faculty, Transcatheter Valve Therapeutics (TVT) 2016, June 16-18, 2016, Chicago, Illinois.220. Invited Faculty, 64th Annual Scientific Session of the Japanese College of Cardiology, September 23-25, 2016, Tokyo, Japan.221. Invited Faculty, TCT 2016, October 29-November 2, 2016, Washington, DC.222. Invited Faculty, AHA 2016, November 12-16, 2016, New Orleans, LA.223. Invited Faculty, CSI Annual Conference 2016, December 2-10, 2016, Cochin, India.

Teaching/Mentoring Activities:

CSMC Teaching Activities

Weekly Cardiac Cath ConferenceConsults at the outpatient clinic at the Pavilion Bldg.

Publications:

A. RESEARCH PAPERS (PEER REVIEWED)

1. Makkar RR, Fromm BS, Steinmann RT, Meissner MD, Lehmann MH. Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. JAMA 1993;270:2590-2597.

2. Spears JR, Yellayi SS, Makkar RR, Nallamothu N, et al. Effects of thermal exposure on binding of heparin in vitro to the arterial wall and to clot and on the chronic angiographic luminal response to local application of a heparin film during angioplasty in an in vivo rabbit model. Lasers in Surgery and Medicine 1994;14(4):329.

3. Makkar RR, Eigler N, Forrester JS, Litvack F. Technical aspects of stents which may be temporary or permanent. In Endovascular Stenting (Sigwart, ed) Saunders Publications 1995;32:230-237.

4. Kaul S, Makkar RR, Nakamura M, Litvack FI, Shah PK, Forrester JS, Hutcell TC, Eigler NL: Inhibition of acute stent thrombosis under high-shear flow conditions by a nitric oxide donor, DMHD/NO: an ex vivo porcine arteriovenous shunt study. Circ 1996;94(9):2228-2234.

5. Makkar RR, Litvack F, Eigler NL, Nakamura M, Ivey PA, Forrester JS, Shah PK, Jordan R, Kaul S: Effects of GP IIb/IIIa receptor monoclonal antibody (7E3), heparin and aspirin in an ex vivo canine arteriovenous shunt model of stent thrombosis. Circ 1997;95 (4):1015-1021.

6. Makkar RR, Eigler NL, Kaul S, Nakamura M, Shah PK, Forrester JS, Herbert JM, Litvack F: Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high shear induced stent thrombosis. Eur Heart J 1998;10:1538-1546.

7. Frimmerman AA, Rechavia E, Eigler N, Payton MR, Makkar RR, Litvack FL. Long term followup of a high risk cohort following stent implantation in saphenous vein grafts. J Am Coll Cardiol 1997;30:1277-83.

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8. Frimerman A, Welch PJ, Jin X, Eigler N, Yei S, Forrester J, Honda H, Makkar R, Barber J, Litvack F: Chimeric DNA-RNA hammerhead ribozyme to PCNA reduces stent induced stenosis in a porcine coronary model. Circulation 1999;99:697-703.

9. Makkar R, Whiting J, Li A, Honda H, Fishbein MC, Knapp R, Litvack F, Eigler N: Effects of a ß-emitting liquid isotope (Rhenium188) filled balloon in stented porcine coronaries: an angiographic, intravascular ultrasound and histomorphic follow-up study. Circulation 2000;102:3117-23.

10. Makkar R, Goff B, Eigler N, Sebastian M, Fischell T, Barr L, D’Haem C, Shah PK, Effron MB, Litvack F: Effect of glycoprotein IIb/IIIa inhibition without thrombolytic therapy on reperfusion in acute myocardial infarction: results of ReoMI pilot study. Catheterization and Cardiovascular Interventions 48:430-434, 1999.

11. Eigler N, Whiting J, Li A, Frimerman A, DeFrance A, Makkar R, Fishbein MC, Schwartz RS, Litvack F: Effects of a positron emitting vanadium-48 nitinol stent on experimental restenosis in porcine coronary arteries: An injury-response study. Cardiovascular Radiation Medicine, 1999; 1(3):239-251.

12. Finkelstein A, Makkar R, Doherty TM, Vegesna VR, Liu M, Shukla A, Bergman J, Fishbein M, Hausleiter J, Takizawa K, Rukshin V, Shah PK, Rajavashisth TB: Increased expression of M-CSF following coronary artery balloon injury is inhibited by intracoronary brachytherapy. Circulation 2002;105:2411-2415

13. Hausleiter J, Li AN, Abbey CK, Makkar R , Whiting JS, Eigler N. Validation of the localization of the target tissue for intracoronary brachytherapy. Z Kardiol. 2002;91 Suppl 3:10-6.

14. Pak H, Qayyum M, Lai A, Kim DT, Hamabe A, Miyauchi Y, Lill MC, Takizawa K, Chen LS, Frantzen M, Fishbein MC, Sharifi BG, Chen PS, Makkar R: Mesenchymal stem cell injection induces cardiac nerve sprouting and increased tenascin expression in a swine model of myocardial infarction. J Cardiovasc Electrophysiol. 2003 Aug;14(8):841-8

15. Rukshin V, Santos R, Gheorghiu M, Shah PK, Kar S, Padmanabhan S, Azarbal B, Tsang VT, Makkar R, Samuels B, Lepor N, Geft I, Tabak S, Khorsandi M, Buchbinder N, Eigler N, Cercek B, Hodgson K, Kaul S. A prospective, nonrandomized, open-labeled pilot study investigating the use of magnesium in patients undergoing nonacute percutaneous coronary intervention with stent implantation. J Cardiovasc Pharmacol Ther 2003;8:193-200.

16. Finkelstein A, McClean D, Kar S, Takizawa K, Varghese K, Baek N, Park K, Fishbein MC, Makkar R , Litvack F, Eigler NL. Local drug delivery via a coronary stent with programmable release pharmacokinetics. Circulation 2003;107:777-84.

17. Chen M, Luo H, Miyamoto T, Atar S, Kobal S, Rahban M, Brasch AV, Makkar R , Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ. Correlation of echo-Doppler aortic valve regurgitation index with angiographic aortic regurgitation severity. Am J Cardiol 2003;92:634-5.

18. Noc M, Matetzky S, Domingo M, Kar S, Makkar R, Cercek B, Litvack F: Frequency of incomplete reperfusion in patients with acute myocardial infarction undergoing primary angioplasty. Am J Cardiol, 2002;90:18-21

19. Hausleiter J, Sebastian M, Li AN, Abbey CK, Honda H, Makkar R, Whiting JS, Eigler N: A porcine coronary stent model of increased neointima firmation in the left anterior descending coronary artery. Z Kardiol 2002;91:614-619.

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20. Aboul-Enein F, Kar S, Hayes SW, Sciammarella M, Abidov A, Makkar R, Friedman JD, Eigler N, Berman DS. Influence of angiographic collateral circulation on myocardial perfusion in patients with chronic total occlusion of a single coronary artery and no prior myocardial infarction. J Nucl Med 2004;45):950-5.

21. Finkelstein A, Hausleiter J, Doherty T, Takizawa K, Bergman J, Liu M, Rukshin V, Fishbein M, Eigler N, Shah P, Rajavashisth T, Makkar R . Intracoronary beta-irradiation enhances balloon-injury-induced tissue factor expression in the porcine injury model. Int J Cardiovasc Intervent 2004;6:20-7.

22. Webb JG, Munt B, Makkar RR , Naqvi TZ, Dang N. Percutaneous stent-mounted valve for treatment of aortic or pulmonary valve disease. Catheter Cardiovasc Interv. 2004;63:89-93.

23. Lee MS, Wilentz JR, Makkar RR , Singh V, Nero T, Swistel D, Belsey SJ, Simon C, Rametta S, DeRose J. Hybrid revascularization using percutaneous coronary intervention and robotically assisted minimally invasive direct coronary artery bypass surgery. J Invasive Cardiol 2004.16:419-25.

24. Lee MS, Makkar RR, Singh V, Rametta S, Valania G, Wilentz J. Preprocedural administration of aminophylline does not prevent AngioJet rheolytic thrombectomy-induced bradyarrhythmias. J Invasive Cardiol. 2005;17:19-22.

25.Forrester JS, Makkar R, Shah PK. Increasing high-density lipoprotein cholesterol in dyslipidemia by cholesteryl ester transfer protein inhibition: an update for clinicians. Circulation. 2005 Apr 12;111(14)1847-54

26. Lee MS, Rametta S, Aragon J, Khan A, Wilentz J, Singh V, Levitt H, Kamra A, Valania G, Makkar R. New heparin dosing regimen for diabetics undergoing percutaneous coronary intervention. J Invasive Cardiol. 2005 May;175(5):248-50.

27. Aragon J, Lee MS, Makkar RR. Percutaneous left ventricular assist device. TandemHeart for high risk coronary intervention. Cathet Cardiovasc Interv. 2005 Jul;65(3):346-52.

28. Lee MS, Shah AP, Jamali A, Makkar RR. Drug-Eluting Stenting is Superior to Bare-Metal Stenting in Saphenous Vein Grafts:Results from the Cedars-Sinai Percutaneous Revascularization (CPR) Registry. Cathet Cardiovasc Interv. 2005 Dec;66(4):507-11.

29. Makkar RR, Price MJ, Lill M, Frantzen M, Takizawa K, Kleisli T, Zheng J, Kar S, McClelan R, Miyamota T, Bick-Forrester J, Fishbein MC, Shah PK, Forrester JS, Sharifi B, Chen PS, Qayyum M. Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Ther. 2005 Dec;10(4):225-33.

30. Price MJ, Chou CC, Frantzen M, Miyamoto T, Kar S, Lee S, Shah PK, Martin BJ, Lill M. Forrester JS, Chen PS, Makkar RR. Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiologic properties. Int J Cardiol. 2006 Aug 10;111(2):231-9.

31. Lee MS, Shah AP, Dang N, Berman D, Forrester J, Shah PK, Aragon J, Jamal F. Makkar RR. Coronary sinus is dilated and outwardly displaced in patients with mitral regurgitation: quantitative angiographic analysis. Catheter Cardiovasc Interv. 2006 Mar;67(3):490-4.

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32. Lee MS, Kapoor N, Jamal F, Czer L, Aragon J, Forrester J, Kar S, Dohad S, Kass R, Eigler N, Trento A, Shah PK, Makkar RR. Comparison of coronary artery bypass surgery with percutaneous coronary interventin with drug-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2006 Feb 21;474(4):864-70.

33. Jamali AH, Lee MS, Makkar RR. Coronary perforation after percutaneous coronary intervention successfully treated with local thrombin injection. J Invasive Cardiol. 2006 Apr;18(4):E143-5.

34. Forrester JS, Lee MS, Kappor N, Makkar RR. The Janus face of drug-eluting stents. J Am Coll Cardiol. 2006 Jul 18;48(2):375-6.

35. Lee SS, Naqvi TZ, Forrester J, Cattley R, Shah A, Frantzen M, Miyamoto T, Kaufman S, Price MJ, Lill M, Makkar RR. The effect of granulocyte colony stimulating factor on regional and global myocardial function in the porcine infarct model. Int J Cardiol. 2006 Aug 2.

36. Kupferwasser LI, Lee MS, Schapira JN, Makkar RR. Percutaneous coronary intervention in unprotected left main disease: a status report. Minerva Cardioangiol. 2006;54(5):633-41.

37. Forrester JS, Shah PK, Makkar RR. Myocardial regeneration by stem cells: seeing the unseeable. J Am Coll Cardiol. 2006 Oct 17;48(8):1722-4.

38. Lee MS, Makkar RR. Percutaneous left ventricular support devices. Cardiol Clin. 2006 May;24(2):265-75.

39. Sharma S, Makkar R, Lardizabal J. Intracoronary administration of abciximab during percutaneous coronary interventions: should this be the routine and preferred approach? J Cardiovasc Pharmacol Ther. 2006 Jun;11(2):136-41.

40. Kupferwasser LI, Amorn A, Kapoor N, Lee MS, Kar S, Cercek B, Dohad S, Mirocha J, Forrester JS, Shah PK, Makkar RR. Comparison of drug-eluting stents with bare metal stents in unselected patients with acute myocardial infarction. Catheterization and Cardiovascular Interventions 2007 Jul 1;70:1-8.

41. Lee MS, Jamal F, Kedia G, Chang G, Kapoor N, Forrester J, Czer L, Zimmer R, Derobertis M, Trento A, Makkar RR. Comparison of bypass surgery with drug-eluting stents for diabetic patients with multivessel disease. Int J Cardiol 2007, Feb 9.

42. Lee MS, Jurewitz D, Aragon J, Forrester J, Makkar RR, Kar S. Stent fracture associated with drug-eluting stents: clinical characteristics and implications. Catheter Cardiovasc Interv 2007 Feb 15;69(3):387-94.

43. Anthony J. White, Gautam Kedia, James M. Mirocha, Michael S. Lee, James S Forrester, Walter C Morales, Suhail Dohad, Saibal kar, Lawrence S. Czer, Gregory P. Fontana, Alfredo Trento, Prediman K. Shah, and Raj R. Makkar: Comparison of Coronary Artery Bypass Surgery and Percutaneous Drug-Eluting Stent Implantation for Treatment of Left Main Coronary Artery Stenosis. J. Am. Coll. Cardiol. Intv. 2008;1;236-245

44. James S. Forrester, Anthony J. White, Satoshi Matsushita, Tarun Chakravarty, and Raj R. Makkar. New Paradigms of Myocardial Regeneration Post-Infarction: Tissue Preservation, Cell Environment, and Pluripotent Cell Sources. J Am Coll Cardiol Intv 2009;2 1-8

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45. Brett M. Wertmann, Victor Y. Cheng, Saibal Kar, Heidi Gransar, Ryan A. Berg, Hursh Naik, Rajendra Makkar, John D. Friedman, Jay N. Schapira, Daniel S. Berman: Characterization of complex coronary artery stenosis morphology by coronary computed tomographic angiography. JACC: Cardiovascular Imaging 2009; 2(8):950-958.

46. Darryl R. Davis, Yiqiang Zhang, Rchel R. Smith, Ke Cheng, John Terrovitis, Konstantinos Malliaras, Tao-sheng Li, Anthony J White, Raj Makkar and Eduardo Marban. Validation of the cardiosphere method to culture cardiac progenitor cells

from myocardial tissue. PLoS One. 2009;4(9):e7195.47. Dixon SR, Henriques JP, Mauri L, Sjauw K, Civitello A, Kar B, Loyalka P, Resnic

FS, Teirstein P, Makkar R, Palacios IF, Collins M, Moses J, Benali K, O'Neill WW. A prospective feasibility trial investigating the use of the Impella 2.5 system in patients undergoing high-risk percutaneous coronary intervention (The PROTECT I Trial): initial U.S. experience. JACC Cardiovasc Interv. 2009 Feb;2(2):91-6.

48. Forrester JS, Makkar RR, Marbán E. Long-term outcome of stem cell therapy for acute myocardial infarction: right results, wrong reasons. J Am Coll Cardiol. 2009 Jun 16;53(24):2270-2. 49. Hursh Naik MD; Anthony J. White MBBS, PhD; Tarun Chakravarty MD; James Forrester, MD, FACC; Gregory Fontana, MD, FACS; Saibal Kar, MD, FACC, FSCAI; Robert E. Weiss PhD; Raj Makkar, MD, FSCAI. A meta-analysis of 3773 patients treated with percutaneous coronary intervention or surgery for unprotected left main coronary artery stenosis. JACC Cardiovasc Interv. 2009 Aug;2(8):739-47.50. Chakravarty T, White AJ, Buch M, Naik H, Doctor N, Schapira J, Kar S, Forrester JS, Weiss RE, Makkar R. Meta-analysis of incidence, clinical characteristics and implications of stent fracture. Am J Cardiol. 2010 Oct 15;106(8):1075-80.51. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S; PARTNER Trial Investigators. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med. 2010 Oct 21;363(17):1597-607. Epub 2010 Sep 22. 52. Rangappa S, Makkar R, Forrester J. Review article: current status of myocardial regeneration: new cell sources and new strategies. J Cardiovasc Pharmacol Ther. 2010 Dec;15(4):338-43. 53. Thompson KA, Kar S, Makkar R, Victor RG. Drug-resistant hypertension: is renal sympathetic denervation the answer? Curr Cardiol Rep. 2011 Apr;13(2):93-5. 54. Lee ST, White AJ, Matsushita S, Malliaras K, Steenbergen C, Zhang Y, Li TS, Terrovitis J, Yee K, Simsir S, Makkar R, Marbán E. Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction. J Am Coll Cardiol. 2011 Jan 25;57(4):455-65. 55. Chakravarty T, Buch MH, Naik H, White AJ, Doctor N, Schapira J, Mirocha JM, Fontana G, Forrester JS, Makkar R. Predictive accuracy of SYNTAX score for predicting long-term outcomes of unprotected left main coronary artery revascularization. Am J Cardiol. 2011 Feb 1;107(3):360-6.

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56. Jilaihawi H, Makkar R, Hussaini A, Trento A, Kar S. Contemporary application of cardiovascular hemodynamics: transcatheter mitral valve interventions. Cardiol Clin. 2011 May;29(2):201-9. 57. Jilaihawi H, Kar S, Doctor N, Fontana G, Makkar R. Contemporary application of cardiovascular hemodynamics: transcatheter aortic valve interventions. Cardiol Clin. 2011 May;29(2):211-22.58. Jilaihawi H, Doumanian A, Stegic J, Fontana G, Makkar R. Transcatheter Aortic Valve Implantation: Patient Selection and Procedural Considerations. Future Medicine. 2011;7(4):499-509.59. Aminzadeh MA, White AJ, Forrester JS, Matsushita S, Makkar RR. Overcoming the Barriers to Stem Cell Therapy [transcript]. Cardiosource Web Site, American College of Cardiology Foundation. Accessed November 10, 200960. Anthony J. White, Rachel R. Smith, Satoshi Matsushita, Tarun Chakravarty, Lawrence S. Czer, Kevin Burton, Ernst R. Schwarz, Darryl R. Davis, Qi Wang, Nancy L. Reinsmoen, James S. Forrester, Eduardo Marbán, Raj Makkar. Intrinsic cardiac origin of human cardiosphere-derived cells. European Heart Journal; Manuscript doi:10.1093/eurheart/ehr172. June 9, 2011.61. Tarun Chakravarty, Ryan P. Morrissey, Brett Wertman, Jesse Naghi, Stanley Chou, Pavel Goykhman, Sean Hirota, Niraj Doctor, James Mirocha, James S. Forrester, Raj Makkar. Comparison of Drug-eluting Stents to Bare Metal Stents for Saphenous Vein Graft Stenosis: 4-year Follow-up Analysis. (Accepted: Catheterization and Cardiovascular Interventions; Manuscript ID: CCI-11-0041.R1). 62. Craig R. Smith, MD, Martin B. Leon, MD, Michael J. Mack, MD, D. Craig Miller, MD, Jeffrey W Moses, MD, Lars G Svensson, MD, PhD, E. Murat Tuzcu, MD, John G. Webb MD, Gregory P Fontana, MD, Raj R Makkar, MD, Mathew Williams, MD, Todd Dewey, MD, Samir Kapadia, MD, Vasilis Babaliaros, MD, Vinod H Thourani, MD, Paul Corso, MD, August D Pichard, MD, Joseph E Vavaria, MD, Howard C Herrmann, MD, Jodi J Akin, MS, William N Anderson, PhD, Duolao Wang, PhD, and Stuart J Pocock, PhD, for the PARTNER Trial Investigators. Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients. The New England Journal of Medicine2011;364:2187-98.63. Reynolds MR, Magnuson EA, Lei Y, Leon MB, Smith CR, Svensson LG, Webb JG, Babaliaros VC, Bowers BS, Fearon WF, Herrmann HC, Kapadia S, Kodali SK, Makkar RR, Pichard AD, Cohen DJ; Placement of Aortic Transcatheter Valves (PARTNER) Investigators. Health-related quality of life after transcatheter aortic valve replacement in inoperable patients with severe aortic stenosis. Circulation. 2011 Nov 1;124(18):1964-72 64. Makkar RR, Fontana GP, Jilaihawi H, Kapadia S, Pichard AD, Douglas PS, Thourani VH, Babaliaros VC, Webb, JG, Herrmann HC, Bavaria JE, Kodali S, Brown DL, Bowers B, Dewey TM, Svensson LG, Tuzcu M, Moses JW, Williams MR, Siegel RJ, Akin JJ, Anderson WN, Pocock S, Smith CR, Leon MB; the PARTNER Trial investigators: Transcatheter Aortic-Valve Replacement for Inoperable Severe Aortic Stenosis. N Engl J Med, 2012, Mar 26.

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65. Kodali SK, Williams MR, Smith CR, Svensson LG, Webb JG, Makkar RR, Fontana GP, Dewey TM, Thourani VH, Pichard AD, Fischbein M, Szeto WY, Lim S, Greason KL, Teirstein PS, Malaisrie SC, Douglas PS, Hahn RT, Whisenant B, Zajarias A, Wand G, Akin JJ, Anderson WN, Leon MB, The PARTNER Trial Investigators: Two- Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement. N Engl J Med 2012, Mar 26.66. Chakravarty T, Morrissey RP, Wertman B, Naghi J, Chou S, Goykhman P, Doctor N, Mirocha J, Forrester JS, Makkar R. Comparison of long-term outcomes of drug-eluting stents and bare metal stents for saphenous vein graft stenosis. Catheter Cardiovasc Interv. 2012 May 1;79(6):903-9.67. Alaide Chieffo, Emanuele Meliga, Azee Latib, Seung-Jung Park, Yoshinobu Onuma, Piera Capranzano, Marco Valgimigli, Sanda Jegere, Raj R Makkar, Igor Palacios, Young-Hak Kim, Pawel Buszman, Tarun Chakravarty, Imad Sheiban, Roxana Mehran, Christoph Naber, Ronan Margey, Arvind Agnihotri, Sebastiano Marra, Davide Capodanno, Martin Leon, Jeffrey Moses, Jean Fajadet, Thierry Lefevre, Marie-Claude Morice, Andrejs Erglis, Corrado Tamburino, Ottavio Alfieri, Patrick Serruys, Antonio Colombo: Drug-Eluting Stents for Left Main Coronary Artery Disease. J Am Coll Cardiol Intv 2012;5:718-27.68. Généreux P, Webb JG, Svensson LG, Kodali SK, Satler LF, Fearon WF, Davidson CJ, Eisenhauer AC, Makkar RR, Bergman GW, Babaliaros V, Bavaria JE, Velazquez OC, Williams MR, Hueter I, Xu K, Leon MB; PARTNER Trial Investigators: Vascular Complications After Transcatheter Aortic Valve Replacement: Insights From the PARTNER (Placement of AoRTic TraNscathetER Valve) Trial. J Am Coll Cardiol. 2012 Sep 18;60(12):1043-52. 69. Chieffo A, Meliga E, Latib A, Park SJ, Onuma Y, Capranzano P, Valgimigli M, Jegere S, Makkar RR, Palacios IF, Kim YH, Buszman PE, Chakravarty T, Sheiban I, Mehran R, Naber C, Margey R, Agnihotri A, Marra S, Capodanno D, Leon MB, Moses JW, Fajadet J, Lefevre T, Morice MC, Erglis A, Tamburino C, Alfieri O, Serruys PW, Colombo A. Drug-eluting stent for left main coronary artery disease. The DELTA registry: a multicenter registry evaluating percutaneous coronary intervention versus coronary artery bypass grafting for left main treatment. JACC Cardiovasc Interv. 2012 Jul;5(7):718-27.70. Willson AB, Rodès-Cabau J, Wood DA, Leipsic J, Cheung A, Toggweiler S, Binder RK, Freeman M, DeLarochellière R, Moss R, Nombela-Franco L, Dumont E, Szummer K, Fontana GP, Makkar R, Webb JG. Transcatheter aortic valve replacement with the St. Jude Medical Portico valve: first-in-human experience.J Am Coll Cardiol. 2012 Aug 14;60(7):581-6. doi: 10.1016/j.jacc.2012.02.045. 71. Jilaihawi H, Chakravarty T, Weiss RE, Fontana GP, Forrester J, Makkar RR. Meta- analysis of complications in aortic valve replacement: comparison of Medtronic- Corevalve, Edwards-Sapien and surgical aortic valve replacement in 8,536 patients. Catheter Cardiovasc Interv. 2012 Jul 1;80(1):128-38. 72. Jilaihawi H, Kashif M, Fontana G, Furugen A, Shiota T, Friede G, Makhija R, Doctor N, Leon MB, Makkar RR. Cross-sectional computed tomographic assessment improves accuracy of aortic annular sizing for transcatheter aortic valve replacement and reduces the incidence of paravalvular aortic regurgitation. J Am Coll Cardiol. 2012 Apr 3;59(14):1275-86.

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73. Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marbán L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marbán E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet. 2012 Mar 10;379(9819):895-904. 74. Kenny D, Hijazi ZM, Kar S, Rhodes J, Mullen M, Makkar R, Shirali G, Fogel M, Fahey J, Heitschmidt MG, Cain C. Percutaneous implantation of the Edwards SAPIEN transcatheter heart valve for conduit failure in the pulmonary position: early phase 1 results from an international multicenter clinical trial. J Am Coll Cardiol. 2011 Nov 15;58(21):2248-56.75. Hasan Jilaihawi, Niraj Doctor, Mohammad Kashif, Tarun Chakravarty, Asim Rafique, Moody Makar, Azusa Furugen, Mamoo Nakamura, James Mirocha, Mitch Gheorghiu, Jasminka Stegic, Kazuaki Okuyama, Daniel J.Sullivan, Robert Siegel, James K. Min, Swaminatha V. Gurudevan, Gregory Fontana, Wen Cheng, Gerald Friede, Takahiro Shiota, Raj R Makkar. Aortic Annular Sizing for Transcatheter Aortic Valve Replacement using Cross-Sectional Three-Dimensional Transesophageal Echocardiography. J Am Coll Cardiol. 2013;61(9):908-91676. Chakravarty T, Jilaihawi H, Doctor N, Fontana G, Forrester J, Cheng W, Makkar R. Complications after Transfemoral Transcatheter Aortic Valve Replacement with a Balloon-expandable Prosthesis: The Importance of Preventative Measures and Contingency Planning. Catheter Cardiovasc Interv. 2013 Feb 21. 77. Okuyama K, Jilaihawi H, Makkar R.The Buddy Balloon for Transcatheter Aortic ValveReplacement: Insights from Computed Tomographic assessment of the Aortic Valvular Complex. J Invasive Cardiol. 2013;25(9):468-470. 78. Chakravarty T, Jilaihawi H, Nakamura M, Kar S, Cheng W, Makkar R. Pre-emptive Positioning of a Coronary Stent in the Left Anterior Descending Artery for Left Main Protection: A Prerequisite for Transcatheter Aortic Valve-in-Valve Implantation for Failing Stentless Bioprostheses? Catheter Cardiovasc Interv. 2013 Oct 1;82(4):E630-6. doi: 10.1002/ccd.25037. Epub 2013 Jul 179. Makkar RR, Jilaihawi H, Chakravarty T, Fontana GP, Kapadia S, Babaliaros V, Cheng W, Thourani VH, Bavaria J, Svensson L, Kodali S, Shiota T, Siegel R, Tuzcu EM, Xu K, Hahn RT, Herrmann HC, Reisman M, Whisenant B, Lim S, Beohar N, Mack M, Teirstein P, Rihal C, Douglas PS, Blackstone E, Pichard A, Webb JG, Leon MB. Determinants and Outcomes of Acute Transcatheter Valve-in-Valve Therapy or Embolization:A Study of Multiple Valve Implants in the US PARTNER trial. J Am Coll Cardiol. 2013 May 15. doi:pii:SO735-1097(13)01879-2. 1 0.1016/j.jacc.2013.04.037. 80. Ribeiro HB, Webb JG, Makkar RR, Cohen MG, Kapadia SR, Kodali S, Tamburino C, Barbanti M, Chakravarty T, Jilaihawi H, Paradis JM, de Brito FS Jr, Cánovas SJ, Cheema AN, de Jaegere PP, del Valle R, Chiam PT, Moreno R, Pradas G, Ruel M, Salgado-Fernández J, Sarmento-Leite R, Toeg HD, Velianou JL, Zajarias A, Babaliaros V, Cura F, Dager AE, Manoharan G, Lerakis S, Pichard AD, Radhakrishnan S, Perin MA, Dumont E, Larose E, Pasian SG, Nombela-Franco L, Urena M, Tuzcu EM, Leon MB, Amat-Santos IJ, Leipsic J, Rodés-Cabau J. Predictive factors, management, and clinical outcomes of coronary obstruction following transcatheter aortic valve implantation: insights from a large multicenter registry. J Am Coll Cardiol. 2013 Oct

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22;62(17):1552-62. doi: 10.1016/j.jacc.2013.07.040. Epub 2013 Aug 14. 81. Makkar R, Jilaihawi H et al. Early and Late Outcomes of Transcatheter Valve-in- Valves for Failed BalloonExpandable Transcatheter Aortic Valves in the US PARTNER trial. Journal of American College of Cardiology 82. Jilaihawi H et al. Thrombocytopenia after Contemporary Therapies for Severe Aortic Stenosis. Journal of American College of Cardiology Intervention83. Konstantinos Malliaras, Raj R Makkar, Rachel R Smith, Ke Cheng, Edwin Wu, Robert O Bonow, Linda Marban, Adam Mendizabal, Eugenio Cingolani, Peter V Johnston, Gary Gerstenblith, Karl H Schuleri, Albert C Lardo, Eduardo Marban: Intracoronary cardiosphere-derived cells after myocardial infarction: evidence for therapeutic regeneration in the final 1-year results of the CADUCEUS trial. J Am Coll Cardiol.2014 Jan 21;63(2):110-22. doi: 10.1016/j.jacc.2013.08.724. Epub 2013 Sep 11.84. Rostamian A, Makkar R, Jilaihawi H , Chakravarty T, Fontana G, Kapadia S, Babaliaros V , Cheng W , Thourani V, Bavaria JE, Svensson L, Kodali SK, Shiota T, Siegel RJ , Tuzcu EM, Xu K , Hahn R, Herrmann H, Reisman M, Whisenant B, Lim S, Beohar N , Mack M , Teirstein P, Rihal C, Douglas P, Blackstone E, Pichard AD, Webb J, Leon M. Determinants and Outcomes of Acute Transcatheter Valve-in-Valve Therapy or Embolization: A Study of Multiple Valve Implants in the US PARTNER Trial. Journal of the American College of Cardiology 62:418-430, 201385. Rostamian A, Rathod A, Makkar RR, Siegel RJ. Three-Dimensional Echocardiographic Assessment of Patent Foramen ovale in Platypnea-Orthodeoxia. Echocardiography. 2013 Jun 25. doi: 10.1111/echo.12265. 86. Okuyama K, Jilaihawi H, Makkar RR. Leaflet length and left main coronary artery occlusion following transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2013 Jun 14. doi: 10.1002/ccd.25059. 87. Barbanti M, Yang TH, Rodés-Cabau J, Tamburino C, Wood DA, Jilaihawi H, Blanke P, Makkar RR, Latib A, Colombo A, Tarantini G, Raju R, Binder RK, Nguyen G, Freeman M, Ribeiro HB, Kapadia S, Min J, Feuchtner G, Gurtvich R, Alqoofi F, Pelletier M, Ussia GP, Napodano M, de Brito FS Jr, Kodali S, Norgaard BL, Hansson NC, Pache G, Canovas SJ, Zhang H, Leon MB, Webb JG, Leipsic J: Anatomical and Procedural Features Associated with Aortic Root Rupture During Balloon-Expandable Transcatheter Aortic Valve Replacement. Circulation. 2013 Jun 7. 88. Makkar R, Jilaihawi et al. Stratification of Outcomes after Transcatheter Aortic Valve Replacement According to Inoperability by Technical Versus Clinical Criteria" – JACC061413-273089. Mamoo Nakamura, Tarun Chakravarty, Hasan Jilaihawi, Niraj Doctor, Suhail Dohad, Gregory Fontana, Wen Cheng and Raj R. Makkar. Complete percutaneous approach for arterial access in transfemoral transcatheter aortic valve replacement – A comparison with surgical cutdown and closure. Catheter Cardiovasc Interv. 19 JUL 2013 09:55AM EST | DOI: 10.1002/ccd.2513090. Samir Kapadia, E. Murat Tuzcu, Raj Makkar, Lars Svensson, Shikhar Agarwal, Susheel Kodali, Gregory P. Fontana, John Webb, Michael Mack, Vinod Thourani, Vasilis Babaliaros, Howard Herrmann, Wilson Szeto, Augusto Pichard, Mathew Williams, William N. Anderson, Jodi Akin, D. Craig Miller, Craig Smith, and Martin Leon: Long-term Outcomes of Inoperable Patients with Aortic Stenosis Randomized To Transcatheter Aortic Valve Replacement or Standard Therapy.

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CIRCULATIONAHA/2014/009834R191. Vinod Thourani, Vasilis Babaliaros, Susheel Kodali, Raj Makkar, Gregory Fontana, Todd Dewey, Michael Mack, John G. Webb, Lars Svensson, E. Murat Tuzcu, Samir Kapadia, Augusto Pichard, Howard Herrmann, Wilson Szeto, D. Craig Miller, Pamela Douglas, William Anderson, Jodi Akin, Craig Smith, and Martin Leon. Three-Year Outcomes from the PARTNER Trial in High-Risk Patients with Aortic Stenosis Treated with Transcatheter or Surgical Aortic Valve Replacement. Circulation 201492. Makkar RR, Smith RR, Czer LS, Russell SD, Gerstenblith G, Marbán E. Letter by makkar et Al regarding article, "cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions". Circ Res. 2014 Nov 7;115(11)93. Konstantinos Malliaras equal contributor, Hideaki Kanazawa equal contributor, Kristine Yee equal contributor, Ke Cheng, Daniel J. Luthringer, Chak-Sum Ho, Kentaro Takayama, Naoto Minamino, James F. Dawkins, Supurna Chowdhury, Doan Trang Duong, Jeffrey Seinfeld, Ryan C. Middleton, Rohan Dharmakumar, Debiao Li, Linda Marbán, Raj R. Makkar, Eduardo Marbán. Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy. Published: December 02, 2014 •DOI: 10.1371/journal.pone.011380594. Hirotsugu Mihara, Kentaro Shibayama, Hasan Jilaihawi, Yuji Itabashi, Javier Berdejo, Hiroto Utsunomiya, Robert Siegel, Raj Makkar, Takahiro Shiota: Assessment of Post-Procedural Aortic Regurgitation after Transcatheter Aortic Valve Replacement: An Intraprocedural Transeshophageal Echocardiography Study”. Submitted to JACC95 . Okuyama K, Jilaihawi H, Kashif M, Takahashi N, Chakravarty T, Pokhrel H, Patel J, Forrester JS, Nakamura M, Cheng W, Makkar RR. Transfemoral access assessment for transcatheter aortic valve replacement: evidence-based application of computed tomography over invasive angiography. Circ Cardiovasc Imaging. 2014 Dec 31;8(1). pii: e001995. doi: 10.1161/CIRCIMAGING.114.001995. Print 2015 Jan 30. PMID: 2555249096. Jilaihawi H, Wu Y, Yang Y, Xu L, Chen M, Wang J, Kong X, Zhang R, Wang M, Lv B, Wang W, Xu B, Makkar RR, Sievert H, Gao R. Morphological characteristics of severe aortic stenosis in China: Imaging corelab observations from the first Chinese transcatheter aortic valve trial. Catheter Cardiovasc Interv. 2015 Jan 29. doi: 10.1002/ccd.25863. [Epub ahead of print]. PMID: 2563049497. Nazif TM, Dizon JM, Hahn RT, Xu K, Babaliaros V, Douglas PS, El-Chami MF, Herrmann HC, Mack M, Makkar RR, Miller DC, Pichard A, Tuzcu EM, Szeto WY, Webb JG, Moses JW, Smith CR, Williams MR, Leon MB, Kodali SK; PARTNER Publications Office. Predictors and Clinical Outcomes of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement: The PARTNER (Placement of AoRtic TraNscathetER Valves) Trial and Registry. JACC Cardiovasc Interv. 2015 Jan;8(1 Pt A):60-9. doi: 10.1016/j.jcin.2014.07.022. PMID: 2561681998. Makkar RR, Jilaihawi H, Mack M, Chakravarty T, Cohen DJ, Cheng W, Fontana GP, Bavaria JE, Thourani VH, Herrmann HC, Pichard A, Kapadia S, Babaliaros V, Whisenant BK, Kodali SK, Williams M, Trento A, Smith CR, Teirstein PS, Cohen MG, Xu K, Tuzcu EM, Webb JG, Leon MB. Stratification of outcomes after transcatheter aortic valve replacement according to surgical inoperability for technical versus clinical

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reasons. J Am Coll Cardiol. 2014 Mar 11;63(9):901-11. doi: 16/j.jacc.2013.08.1641. Epub 2013 Oct 23.99. Nazif TM, Williams MR, Hahn RT, Kapadia S, Babaliaros V, Rodés-Cabau J, Szeto WY, Jilaihawi H, Fearon WF, Dvir D, Dewey TM, Makkar RR, Xu K, Dizon JM, Smith CR, Leon MB, Kodali SK Clinical implications of new-onset left bundle branch block after transcatheter aortic valve replacement: analysis of the PARTNER experience..Eur Heart J. 2014 Jun 21;35(24):1599-607. doi:10.1093/eurheartj/eht376. Epub 2013 Oct 30.100. Shibayama K, Harada K, Berdejo J, Mihara H, Tanaka J, Gurudevan SV, Siegel R, Jilaihawi H, Makkar RR, Shiota T. Effect of transcatheter aortic valve replacement on the mitral valve apparatus and mitral regurgitation: real-time three-dimensional transesophageal echocardiography study. Circ Cardiovasc Imaging. 2014 Mar;7(2):344-51. doi: 10.1161/CIRCIMAGING.113.000942. Epub 2014 Jan 28.101.Beigel R, Siegel RJ, Kahlon RS, Jilaihawi H, Cheng W, Makkar RR. Transcatheter aortic valve implantation for a failed bio-bentall in patients with Marfan syndrome Cardiology. 2014;128(1):9-12. doi: 10.1159/000357265. Epub 2014 Feb 5.102. Jilaihawi H, Doctor N, Chakravarty T, Kashif M, Mirocha J, Cheng W, Lill M, Nakamura M, Gheorghiu M, Makkar R. Major thrombocytopenia after balloon- expandable transcatheter aortic valve replacement: Prognostic implications and comparison to surgical aortic valve Catheter Cardiovasc Interv. 2014 Feb 12. doi: 10.1002/ccd.25430.103. Nazif TM, Williams MR, Hahn RT, Kapadia S, Babaliaros V, Rodés-Cabau J, Szeto WY, Jilaihawi H, Fearon WF, Dvir D, Dewey TM, Makkar RR, Xu K, Dizon JM, Smith CR, Leon MB, Kodali SK. Clinical implications of new-onset left bundle branch block after transcatheter aortic valve replacement: analysis of the PARTNER experience. Eur Heart J. 2014 Jun 21;35(24):1599-607.104. Jilaihawi H, Makkar RR, Kashif M, Okuyama K, Chakravarty T, Shiota T, Friede G, Nakamura M, Doctor N, Rafique A, Shibayama K, Mihara H, Trento A, Cheng W, Friedman J, Berman D, Fontana GP. A revised methodology for aortic-valvar complex calcium quantification for transcatheter aortic valve implantation. Eur Heart J Cardiovasc Imaging. 2014 Dec;15(12):1324-32.105. Okuyama K, Jilaihawi H, Mirocha J, Nakamura M, Ramzy D, Makkar R, Cheng W. Alternative access for balloon-expandable transcatheter aortic valve replacement: Comparison of the transaortic approach using right anterior thoracotomy to partial J-sternotomy. J Thorac Cardiovasc Surg. 2015 Mar;149(3):789-97.106. Jilaihawi H, Chakravarty T, Shiota T, Rafique A, Harada K, Shibayama K, Doctor N, Kashif M, Nakamura M, Mirocha J, Rami T, Okuyama K, Cheng W, Sadruddin O, Siegel R, Makkar RR. Heart-rate adjustment of transcatheter haemodynamics Improves the prognostic evaluation of paravalvular regurgitation after transcatheter aortic valve implantation. EuroIntervention. 2014 Dec 16. pii: 20140716-01. 107. Okuyama K, Jilaihawi H, Kashif M, Takahashi N, Chakravarty T, Pokhrel H, Patel J, Forrester JS, Nakamura M, Cheng W, Makkar RR. Transfemoral access assessment for transcatheter aortic valve replacement: evidence- based application of computed tomography over invasive angiography. Circ Cardiovasc Imaging. 2014 Dec 31;8(1).

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108. Dvir D, Leipsic J, Blanke P, Ribeiro HB, Kornowski R, Pichard A, Rodés-Cabau J, Wood DA, Stub D, Ben-Dor I, Maluenda G, Makkar RR, Webb JG. Coronary Obstruction in Transcatheter Aortic Valve-in-Valve Implantation: Preprocedural Evaluation, Device Selection, Protection, and Treatment. Circ Cardiovasc Interv. 2015 Jan;8(1). pii: e002079. doi: 10.1161/CIRCINTERVENTIONS.114.002079. PMID: 25593122109. Kanazawa H, Tseliou E, Malliaras K, Yee K, Dawkins JF, De Couto G, Smith RR, Kreke M, Seinfeld J, Middleton RC, Gallet R, Cheng K, Luthringer D, Valle I, Chowdhury S, Fukuda K, Makkar RR, Marbán L, Marbán E. Cellular Post- Conditioning: Allogeneic Cardiosphere-Derived Cells Reduce Infarct Size and Attenuate Microvascular Obstruction When Administered After Reperfusion in Pigs With Acute Myocardial Infarction. Circ Heart Fail. 2015 Jan 13. pii: CIRCHEARTFAILURE.114.001484. [Epub ahead of print]. PMID: 25587096110. Mihara H, Shibayama K, Berdejo J, Harada K, Itabashi Y, Siegel RJ, Kashif M, Jilaihawi H, Makkar RR, Shiota T. Impact of Device Landing Zone Calcification on Paravalvular Regurgitation after Transcatheter Aortic Valve Replacement: A Real- Time Three-Dimensional Transesophageal Echocardiographic Study. J Am Soc Echocardiogr. 2015 Jan 2. pii: S0894-7317(14)00857-8. doi: 10.1016/j.echo.2014.11.013. [Epub ahead of print]. PMID: 25560483111. Samir Kapadia, E. Murat Tuzcu, Raj Makkar, Lars Svensson, Shikhar Agarwal, Susheel Kodali, Gregory Fontana, John G. Webb, Michael Mack, Vinod Thourani, Vasilis Babaliaros, Howard Herrmann, Wilson Szeto, Augusto Pichard, Mathew Williams, William Anderson, Jodi Akin, D. Craig Miller, Craig Smith, and Martin Leon. When is TAVR Futile? Circulation 2015. IP 192231133253112. Kentaro Shibayama, Hirotsugu Mihara, Hasan Jilaihawi, Javier Berdejo, Kenji Harada, Yuji Itabashi, Robert Siegel, Raj Makkar, Takahiro Shiota: Three-Dimensional Assessment of Features Associated with Transvalvular Aortic Regurgitation after Transcatheter Aortic Valve Replacement: A Real-Time Three-Dimensional Transesophageal Echocardiography Study. JACC: Cardiovascular Imaging 2015.113. Prof Samir R Kapadia, MD, Prof Martin B Leon, MD, Raj R Makkar, MD, Prof E Murat Tuzcu, MD, Prof Lars G Svensson, MD, Susheel Kodali , MD, Prof John G Webb, MD, Prof Michael J Mack, MD, Prof Pamela S Douglas, MD, Prof Vinod H Thourani, MD, Vasilis C Babaliaros, MD, Prof Howard C Herrmann, MD, Wilson Y Szeto, MD, Augusto D Pichard, MD, Mathew R Williams, MD, Gregory P Fontana, MD, Prof D Craig Miller, William N Anderson, PhD, Prof Craig R Smith, MD, for the PARTNER trial investigators, Jodi J Akin*, Michael J Davidson† *J J Akin MS has no affiliations †M J Davidson MD died in January, 2015: 5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial. The Lancet Published Online March 2015.114. Samir Kapadia,,E. Murat Tuzcu,,Raj Makkar, Lars G. Svensson, Shikhar Agarwal, Susheel K. Kodali, Gregory Fontana, John Webb, Michael Mack, Vinod H. Thourani Vasilis Babaliaros, Howard Herrmann, Wilson Y. Szeto, Augusto Pichard Mathew R. Williams, William Anderson, Jodi J. Akin, D. Craig Miller, Craig Smith Martin B. Leon. When is TAVR futile? Circulation 2015.

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transcatheter aortic valve replacement in inoperable, high-risk and intermediate-risk patients with aortic stenosis. Eur Heart J. 2016 Mar 31. pii: ehw112. PMID: 27190101171. Chowdhury SM, Hijazi ZM, Fahey JT, Rhodes JF, Kar S, Makkar R, Mullen M, Cao QL, Shirali GS. Speckle-Tracking Echocardiographic Measures of Right Ventricular Function Correlate With Improvement in Exercise Function After Percutaneous Pulmonary Valve Implantation. J Am Soc Echocardiogr. 2015 Sep;28(9):1036-44. doi: 10.1016/j.echo.2015.05.010. PMID: 26117295172. Abramowitz Y, Maeno Y, Chakravarty T, Kazuno Y, Takahashi N, Kawamori H, Mangat G, Cheng W, Jilaihawi H, Makkar RR. Aortic Angulation Attenuates Procedural Success Following Self-Expandable But Not Balloon-Expandable TAVR. JACC Cardiovasc Imaging. 2016 Jul 8. pii: S1936-878X(16)30361-8. doi: 10.1016/j.jcmg.2016.02.030. PMID: 27424244173. Herrmann HC, Thourani VH, Kodali SK, Makkar RR, Szeto WY, Anwaruddin S, Desai N, Lim S, Malaisrie SC, Kereiakes DJ, Ramee S, Greason KL, Kapadia S, Babaliaros V, Hahn RT, Pibarot P, Weissman NJ, Leipsic J, Whisenant BK, Webb JG, Mack MJ, Leon MB; PARTNER Investigators. One-Year Clinical Outcomes With SAPIEN 3 Transcatheter Aortic Valve Replacement in High-Risk and Inoperable Patients With Severe Aortic Stenosis. Circulation. 2016 Jul 12;134(2):130-40. doi: 10.1161/CIRCULATIONAHA.116.022797. PMID: 27400898174. Hasan Jilaihawi, MDa; Mao Chen, MDb; John Webb, MDc; Dominique Himbert, MDd; Carlos E. Ruiz, MDe; Josep Rodés-Cabau, MDf; Gregor Pache, MDg; Antonio Colombo, MDh; Georg Nickenig, MDi; Michael Lee, MDj; Corrado M, Tamburino C, Sievert H, Abramowitz Y, Tarantini G, Alqoofi F, Chakravarty T, Kashif M, Takahashi N, Kazuno Y, Maeno Y, Kawamori H, Chieffo A, Blanke P, Dvir D, Ribeiro HB, Feng Y, Zhao ZG, Sinning JM, Kliger C, Giustino G, Pajerski B, Imme S, Grube E, Leipsic J, Vahanian A, Michev I, Jelnin V, Latib A, Cheng W, Makkar R. A Bicuspid Aortic Valve Imaging Classification for the TAVR Era. JACC Cardiovasc Imaging. 2016 Jun 29. pii: S1936-878X(16)30261-3. doi: 10.1016/j.jcmg.2015.12.022. PMID: 27372022175. Raj R. Makkar, M.D., Gregory Fontana, M.D., Hasan Jilaihawi, M.D., Tarun Chakravarty, M.D., Klaus F. Kofoed, M.D., D.M.Sc., Ole de Backer, M.D., Ph.D., Federico M. Asch, M.D., Carlos E. Ruiz, M.D., Niels T. Olsen, M.D., Ph.D., Alfredo Trento, M.D., John Friedman, M.D., Daniel Berman, M.D., Wen Cheng, M.D., Mohammad Kashif, M.D., Vladimir Jelnin, M.D., Chad A. Kliger, M.D., Hongfei Guo, Ph.D., Augusto D. Pichard, M.D., Neil J. Weissman, M.D., Samir Kapadia, M.D., Eric Manasse, M.D., Deepak L. Bhatt, M.D., M.P.H., Martin B. Leon, M.D., and Lars Søndergaard, M.D. Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves. N Engl J Med 2015; 373:2015-2024November 19, 2015DOI: 10.1056/NEJMoa1509233176. Chakravarty T, Makkar RR, Ascheim D, Traverse JH, Schatz R, DeMaria A, Francis GS, Povsic TJ, Smith R, Lima JA, Pogoda JM, Marbán L, Henry TD. ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration (ALLSTAR) trial: Rationale &amp; Design. Cell Transplant. 2016 Aug 18. [Epub ahead of print] PMID: 27543900177. Barbanti M, Webb JG, Tamburino C, Van Mieghem NM, Makkar RR, Piazza N, Latib A, Sinning JM, Won-Keun K, Bleiziffer S, Bedogni F, Kapadia S, Tchetche D, Rodés-Cabau J, Fiorina C, Nombela-Franco L, De Marco F, de Jaegere PP, Chakravarty T, Vaquerizo B, Colombo A, Svensson L, Lange R, Nickenig G,

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Möllmann H, Walther T, Della Rosa F, Elhmidi Y, Dvir D, Brambilla N, Immè S, Sgroi C, Gulino S, Todaro D, Pilato G, Petronio AS, Tamburino C. Outcomes of Redo Transcatheter Aortic Valve Replacement for the Treatment of Postprocedural and Late Occurrence of Paravalvular Regurgitation and Transcatheter Valve Failure. Circ Cardiovasc Interv. 2016 Sep;9(9). pii: e003930. doi: 10.1161/ CIRCINTERVENTIONS. 116.003930. PMID: 27578840178. Natarajan D, Makkar R, MacCarthy P, Eltchaninoff H, Sondergaard L, Prendergast B. Will PARTNER change my practice? Placement of Aortic Transcatheter Valves (PARTNER) 2 Cohort A trial - transcatheter or surgical aortic-valve replacement in intermediate-risk patients. EuroIntervention. 2016 Aug 20;12(6):805-8. PMID: 27542796179. Kalra A, Bhatt DL, Pinto DS, Kirtane AJ, Kapadia SR, Makkar RR, Rihal CS, Kleiman NS, Cutlip DE. Accreditation and funding for a 24-month advanced interventional cardiology fellowship program: A call-to-action for optimal training of the next generation of interventionalists. Catheter Cardiovasc Interv. 2016 Aug 12. doi: 10.1002/ccd.26661. PMID: 27515241180. Okuyama K, Jilaihawi H, Abramowitz Y, Kashif M, Patel J, Pokhrel H, Chakravarty T, Nakamura M, Cheng W, Makkar R. The clinical impact of vascular complications as defined by VARC-1 vs. VARC-2 in patients following transcatheter aortic valve implantation. EuroIntervention. 2016 Aug 5;12(5):e636-42. doi: 10.4244/EIJV12I5A104. PMID: 27497364181. Pyxaras SA, Hunziker L, Chieffo A, Meliga E, Latib A, Park SJ, Onuma Y, Capranzano P, Valgimigli M, Narbute I, Makkar RR, Palacios IF, Kim YH, Buszman PP, Chakravarty T, Sheiban I, Mehran R, Margey R, Agnihotri A, Marra S, Capodanno D, Leon MB, Moses JW, Fajadet J, Lefevre T, Morice MC, Erglis A, Tamburino C, Alfieri O, Serruys PW, Colombo A, Naber CK. Long-term clinical outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for acute coronary syndrome from the DELTA registry: a multicentre registry evaluating percutaneous coronary intervention versus coronary artery bypass grafting for left main treatment. EuroIntervention. 2016 Aug 5;12(5):e623-31. doi: 10.4244/EIJV12I5A102. PMID: 27497362182. Tzikas A, Amrane H, Bedogni F, Brambilla N, Kefer J, Manoharan G, Makkar R, Möllman H, Rodés-Cabau J, Schäfer U, Settergren M, Spargias K, van Boven A, Walther T, Worthley SG, Sondergaard L. Transcatheter Aortic Valve Replacement Using the Portico System: 10 Things to Remember. J Interv Cardiol. 2016 Aug 5. doi: 10.1111/joic.12322. PMID: 27492337183. Chakravarty T, Abramowitz Y, Jilaihawi H, Makkar RR. Leaflet motion abnormality after TAVI: genuine threat or much ado about nothing? EuroIntervention. 2016 Sep 18;12(Y):Y28-32. doi: 10.4244/EIJV12SYA7. PMID: 27640027184. Simonato M, Azadani AN, Webb J, Leipsic J, Kornowski R, Vahanian A, Wood D, Piazza N, Kodali S, Ye J, Whisenant B, Gaia D, Aziz M, Pasala T, Mehilli J, Wijeysundera HC, Tchetche D, Moat N, Teles R, Petronio AS, Hildick-Smith D, Landes U, Windecker S, Arbel Y, Mendiz O, Makkar R, Tseng E, Dvir D. In vitro evaluation of implantation depth in valve-in-valve using different transcatheter heart valves. EuroIntervention. 2016 Sep 18;12(7):909-17. doi: 10.4244/EIJV12I7A149.

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PMID: 27639744185. Regueiro A, Linke A, Latib A, Ihlemann N, Urena M, Walther T, Husser O, Herrmann HC, Nombela-Franco L, Cheema AN, Le Breton H, Stortecky S, Kapadia S, Bartorelli AL, Sinning JM, Amat-Santos I, Munoz-Garcia A, Lerakis S, Gutiérrez-Ibanes E, Abdel-Wahab M, Tchetche D, Testa L, Eltchaninoff H, Livi U, Castillo JC, Jilaihawi H, Webb JG, Barbanti M, Kodali S, de Brito FS Jr, Ribeiro HB, Miceli A, Fiorina C, Dato GM, Rosato F, Serra V, Masson JB, Wijeysundera HC, Mangione JA, Ferreira MC, Lima VC, Carvalho LA, Abizaid A, Marino MA, Esteves V, Andrea JC, Giannini F, Messika-Zeitoun D, Himbert D, Kim WK, Pellegrini C, Auffret V, Nietlispach F, Pilgrim T, Durand E, Lisko J, Makkar RR, Lemos PA, Leon MB, Puri R, San Roman A, Vahanian A, Søndergaard L, Mangner N, Rodés-Cabau J. Association Between Transcatheter Aortic Valve Replacement and Subsequent Infective Endocarditis and In-Hospital Death. JAMA. 2016 Sep 13;316(10):1083-92. doi: 10.1001/jama.2016.12347. PMID: 27623462186. Okuyama K, Chakravarty T, Makkar RR. Percutaneous transapical pseudoaneurysm closure following transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2016 Sep 13. doi: 10.1002/ccd.26494. PMID: 27619932187. Makkar R, Chakravarty T, Jilaihawi H. Transcatheter Aortic Valve Replacement for Bicuspid Aortic Stenosis: Are We Ready for the Challenge? J Am Coll Cardiol. 2016 Sep 13;68(11):1206-8. doi: 10.1016/j.jacc.2016.06.042. PMID: 27609683188. Abramowitz Y, Jilaihawi H, Chakravarty T, Maeno Y, Kawamori H, Kazuno Y, Mangat G, Rami T, Allison Z, Anderson D, Chan L, Cheng W, Makkar RR. Sapien 3 Transcatheter Aortic Valve Implantation With Moderate or Without Predilation. J Invasive Cardiol. 2016 Oct;28(10):421-426. PMID: 27705892189. Cheng R, Vanichsarn C, Patel JK, Currier J, Chang DH, Kittleson MM, Makkar R, Kobashigawa JA, Azarbal B. Long-term clinical and angiographic outcomes of percutanenous coronary intervention with everolimus-eluting stents for the treatment of cardiac allograft vasculopathy. Catheter Cardiovasc Interv. 2016 Nov 10. doi: 10.1002/ccd.26830. PMID: 27862865190. Capodanno D, Gargiulo G, Buccheri S, Chieffo A, Meliga E, Latib A, Park SJ, Onuma Y, Capranzano P, Valgimigli M, Narbute I, Makkar RR, Palacios IF, Kim YH, Buszman PE, Chakravarty T, Sheiban I, Mehran R, Naber C, Margey R, Agnihotri A, Marra S, Leon MB, Moses JW, Fajadet J, Lefèvre T, Morice MC, Erglis A, Alfieri O, Serruys PW, Colombo A, Tamburino C; DELTA Investigators. Computing Methods for Composite Clinical Endpoints in Unprotected Left Main Coronary Artery Revascularization: A Post Hoc Analysis of the DELTA Registry. JACC Cardiovasc Interv. 2016 Nov 28;9(22):2280-2288. doi: 10.1016/j.jcin.2016.08.025. PMID: 27884354191. Kapadia SR, Kodali S, Makkar R, Mehran R, Lazar RM, Zivadinov R, Dwyer MG, Jilaihawi H, Virmani R, Anwaruddin S, Thourani VH, Nazif T, Mangner N, Woitek F, Krishnaswamy A, Mick S, Chakravarty T, Nakamura M, McCabe JM, Satler L, Zajarias A, Szeto WY, Svensson L, Alu MC, White RM, Kraemer C, Parhizgar A, Leon MB, Linke A. Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2016 Oct 27. pii: S0735-1097(16)36768-7. doi: 10.1016/j.jacc.2016.10.023. PMID: 27815101192. Daubert MA, Weissman NJ, Hahn RT, Pibarot P, Parvataneni R, Mack MJ, Svensson

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LG, Gopal D, Kapadia S, Siegel RJ, Kodali SK, Szeto WY, Makkar R, Leon MB, Douglas PS. Long-Term Valve Performance of TAVR and SAVR: A Report From the PARTNER I Trial. JACC Cardiovasc Imaging. 2016 Dec 8. pii: S1936- 878X(16)30895-6. doi: 10.1016/j.jcmg.2016.11.004. PMID: 28017714193. Dangas GD, Weitz JI, Giustino G, Makkar R, Mehran R. Prosthetic Heart Valve Thrombosis. J Am Coll Cardiol. 2016 Dec 20;68(24):2670-2689. doi: 10.1016/j.jacc.2016.09.958. PMID: 27978952

B. RESEARCH PAPERS – PEER REVIEWED (IN PRESS)

1. Abramowitz Y, Chakravarty T, Jilaihawi H, Makkar RR. Update on new devices for transcatheter aortic valve replacement. Accepted for publication. J Struct Heart Dis. 2015

C. RESEARCH PAPERS – PEER REVIEWED (SUBMITTED)

1. Abramowitz Y, Jilaihawi H, Chakravarty T, Kashif M, Matar G, Hariri B, Patel J, Sharma R, Cheng W, Makkar RR. Feasibility and safety of balloon-expandable transcatheter aortic valve implantation with moderate or without predilatation. Under review in EuroIntervention.

2. Abramowitz Y, Jilaihawi H, Chakravarty T, Mangat G , Patel J, Hariri B, Cheng W, Makkar RR. The clinical impact of diabetes mellitus on outcomes after transcatheter aortic valve replacement. Under review in Int J cardiol.

D. RESEARCH PAPERS – NON-PEER REVIEWED (IN PRESS)

E. RESEARCH PAPERS – NON-PEER REVIEWED (SUBMITTED)

CHAPTERS:

1. Eigler N, Whiting JS, Makkar R, Chernomorsky A and Litvack F: Isolated Liquid Beta Source Balloon Radiation Delivery System (Radiant™). In Handbook of Vascular Brachytherapy (Waksman, Serruys, eds). Martin Dunitz 1997;107-110.

2. Makkar RR, Eigler NL, Litvack FL: The role of saline flush in reducing collateral damage during excimer coronary laser angioplasty. In Current Review of Interventional Cardiology (Holmes, Serruys, eds) Churchill Livingston 1997;:51-55.

3. Jamali A, Makkar RR. In Common Clinical Dilemmas in Percutaneous Coronary Interventions (Martinez, Lemos, Ong, Serruys, eds) informa healthcare 2007; 213-223.

4. Sharma S, Makkar R: IC vs IV glycoprotein Iib/IIIa inhibitors. In Pharmacology in the Cath Lab. (Waksman, ed). (in press)

5. Anthony White, Rachel R. Smith, Raj Makkar, and Eduardo Marbán. “Stem cell labeling for delivery and tracking using non-invasive imaging” edited by Joseph Wu and Dara Kraitchman. In Press.6. The textbook will be called: “Stem cell labeling for delivery and tracking using

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non-invasive imaging” edited by Joseph Wu and Dara Kraitchman. The title of our chapter will be: “Cardiology Clinical Stem Cell Applications” by Anthony White, Rachel R. Smith, Raj Makkar, and Eduardo Marbán. In Preparation

7. Hasan Jilaihawi, Raj Makkar, Asma Hussaini, Alfredo Trento and Saibal Kar: Contemporary Application of Cardiovascular Hemodynamics: Transcatheter Mitral Valve Interventions. In Cardiology Clinics (Michael J. Lim, Michael H. Crawford, eds) Saunders an imprint of Elsevier, Inc. May 2011;29 (2); 201-209.8. Hasan Jilaihawi, Saibal Kar, Niraj Doctor, Gregory Fontana and Raj Makkar: Contemporary Application of Cardiovascular hemodynamics: Transcatheter Aortic Valve Interventions. . In Cardiology Clinics (Michael J. Lim, Michael H. Crawford, eds) Saunders an imprint of Elsevier, Inc. May 2011;29 (2); 211-222.9. Anthony J. White, Rachel Ruckdeschel Smith, Raj Makkar, and Eduardo Marban.

In Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging (Dara L. Kraitchman and Joseph C. Wu, eds) CRC Press 2012; (22); 389-404.

10. Hasan Jilaihawi, Tarun Chakravarty and Raj Makkar. Transcatheter Aortic Valve Replacement: What the near-term future holds and what evidence is needed? In Multimodality Imaging for Transcatheter Aortic Valve (Dr. James K. Min, Dr. Jonathan Leipsic, & Dr. Daniel S. Berman). Springer Scinece & Media, London, England. Press 2013.

11. Chakravarty T, Jilaihawi H, Makkar R. Aortic Valve Intervention for Clinical Decision Support: Cardiology. Harvard Medical School. Due to be published in 2013

CHAPTERS (IN PRESS)

LETTERS TO THE EDITOR

REVIEWS:

1. Makkar RR, Litvack F, Eigler N, Forrester JS. Treatment of Vascular Disease with Local Drug Delivery Systems. Cardiologia. 1995;40(9):651-657.

2. Makkar RR, Shah PK. Noninvasive Diagnosis of Reperfusion During Lytic Therapy for Acute MI. The Journal of Myocardial Ischemia. 1995;7:141-151.

3. Makkar RR, Eigler N, Litvack F, Forrester JS. Prevention of Restenosis by Local Drug Delivery. A Review. Journal of Cardiovascular Pharmacology and Therapeutics 1996;1:16-23.

4. Litvack F, Makkar RR: Platelet inhibition with abciximab reduces adverse outcomes in patients undergoing coronary stenting: the evaluation of platelet IIb/IIIa inhibitor for stenting (EPISTENT) Trial. Cardiovascular Reviews & Reports

5. Hausleiter J, Li A, Makkar R, Berman D, Robinson A, Litvack F, Eigler N, Whiting J: Leakage of a liquid 188Re-filled balloon system during intracoronary brachytherapy. A case report. Cardiovascular Radiation Medicine 2000;2 (1):7-10.

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6. Kar S, Makkar R: Percutaneous transluminal septal myocardial ablation: a novel, nonsurgical treatment for sympathetic hypertrophic cardiomyopathy. Rev Cardiovasc Med 2001;2(2):97-102.

7. Sebastian M, Makkar R: Glycoprotein IIb/IIIa receptor antagonists: Clinical pharmacology in cardiovascular diseases of aging. Drugs & Aging 1999;15:207-218.

8. Sharma S, Forrester J, Makkar RM. The SoS trial. Lancet. 2003;361:614-5.9. Sharma S, Makkar RM. Percutaneous intervention on the LIMA: tackling the

tortuosity. J Invasive Cardiol 2003;15:359-62.10. Forrester JS, Price M, Makkar RR . Mending the broken heart. Clin Cardiol

2003;10:449-50.11. Forrester JS, Price MJ, Makkar RR. Stem cell repair of infarcted myocardium: an

overview for clinicians. Circulation 2003;108:1139-45.12. Lee MS, David E, Makkar RR, Wilentz J. Molecular and Cellular Basis of Restenosis

after Percutaneous Coronary Intervention: The Intertwining Roles of Platelets, Leukocytes, and Coagulation-Fibrinolysis System. J Pathol 2004; 203:861-70.

13. Lee MS, Singh V, Wilentz J, Makkar RR. AngioJet rheolytic thrombectomy system. J Invasive Cardiol 2004;16:587-591.

14. Bick-Forrester J, Lee MS, Makkar RR, Forrester JS. Partial restoration of myocardial function and perfusion by cell therapy following myocardial infarction. Current Opin Cardiol 2004; 19:631-7.

15. Goldberg SL, Makkar R, Duckwiler G. New strategies in the percutaneous management of coronary artery fistulae. Catheter Cardiovasc Interv. 2004;61:227-32.

16. Lee MS, Makkar RR. Stem Cell Transplantation in Myocardial Infarction: A status report. Annals of Internal Medicine. 2004;9:729-737.

17. Lee MS, Lill M, Makkar RR. Stem Cell Transplantation in Myocardial Infarction. Reviews in Cardiovascular Medicine. 2004;5:82-98.

18. Toscani MR, Makkar R , Bottorff MB. Quality improvement in the continuum of care: impact of atherothrombosis in managed care pharmacy. J Manag Care Pharm 2004;10(Suppl A):S2-12; S13-6.

19. Lee MS, Nero T, Makkar RR , Wilentz JR. Treatment of coronary aneurysm in acute myocardial infarction with AngioJet thrombectomy and JoStent coronary stent graft.J Invasive Cardiol 2004;16:294-6.

20. Lee S, Bick-Forrester J, Makkar RR, Forrester JS. Stem-cell repair of infarcted myocardium: ready for clinical application? Am Heart Hosp J. 2004;;2:100-6.

21. Jilaihawi H, Makkar RR. Prognostic impact of aortic regurgitation after transcatheter aortic valve implantation. EuroIntervention. 2012 Sep;8 Suppl Q:Q31-3. doi: 10.4244/EIJV8SQA7.

22. Reinthaler M, Empen K, Busch M, Könemann R, Ince H, Felix SB, Jilaihawi H, Chakravarty T, Makkar RR, Franzen O, Loh PH, Ihlemann N, Søndergaard L. How should I treat severe paravalvular leakage after TAVI? EuroIntervention. 2013 Sep;9(5):650-3. doi: 10.4244/EIJV9I5A104.

23. Jilaihawi H*, Abramowitz Y*, Chakravarty T, Mack MJ, Makkar RR. Porcelain aorta: a comprehensive review. Circulation. 2015 Mar 3;131(9):827-36. *Equal contribution.

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EDITORIALS

1. Makkar RR, Lill M, Chen PS. Stem cell therapy for myocardial repair: is it arrhythmogenic? J Am Coll Cardiol 2003;42:2070-2.

ABSTRACTS

1. Makkar RR, Eigler NL, Nakamura M, Litvack FI, Badimon L, Kaul S. Monoclonal antibody to IIb-IIIa receptor (m7E3) is highly effective in inhibiting acute stent thrombosis. Circ 1995;92(8):3291.

2. Makkar RR, Eigler NL, Nakamura M, Litvack FI, Badimon J, Molloy MD, Hutsell T, Kaul S. Marked inhibition of acute stent thrombosis by a novel nitric oxide donor. Circ 1995;92(8):3296.

3. Makkar RR, Sheth S, Yhip P, Luo H, Fishbein MC, Dev V, Eigler NL, and Litvack F. Geometric remodelling predominantly accounts for luminal loss in rabbit iliac artery injury model: A serial intravascular ultrasound study. Circ 1995;92(8):443.

4. Makkar RR, Kaul S, Nakamura M, Dev V, Litvack FI, Park K, McPherson T, Badimon J, Sheth S, Eigler NL. Modulation of stent thrombosis by metal characteristics and shear rate. Circ 1995;92(8):410.

5. Makkar RR, Eigler NL, Nakamura M, Litvack FI, Badimon J, Molloy MD, Hutsell T, Kaul S. Clopidogrel is more effective than aspirin in inhibiting high shear-mediated acute stent thrombosis. JACC 1996;27(2):991-45.

6. Makkar RR, Fromm B, Steinmann R, Miessner M, Lehman M. Female predominance in drug induced Torsade de Pointes. PACE 1991 (Supplement).

7. Makkar RR, Jandhyala R, McMath L, Spears JR. Thermal binding of heparin to arterial tissue during LBA. Clinical Research 1991 (Supplement).

8. Makkar RR, Litvack F, Kaul S, Nakamura M, Fishbein MC, Eigler NL: Microscopic mechanisms of stent thrombosis: role of 7E3 antibody. Circ 1996;94(8):I-260.

9. Makkar RR, Litvack F, Kaul S, Zeng H, Eigler N: High-shear overrides the antithrombotic effects of aspirin on stent thrombosis. JACC 1997;29(2):354A.

10. Eigler N, Whiting J, Makkar RR, Li A, DeFrance A, Frimerman A, Fishbein MC, Litvack F: Effects of beta+ emitting V48 ACT-One nitinol stent on neointimal proliferation in pig coronary arteries. JACC 1997;29(2):237A.

11. Makkar RR, Eigler N, Kaul S, Forrester J, Litvack F: Integrated mechanisms of experimental stent thrombosis. JACC 1997;29(2):94A.

12. Makkar RR, Kaul S, Zeng H, Herbert JM, Litvack F: Clopidogrel, a novel platelet ADP-receptor antagonist inhibits aspirin and ticlopidine-resistant stent thrombosis.JACC 1997;29(2):353A.

13. Frimerman A, Eigler N, Makkar R, Litvack F: Ribozymes to CDC-2 and PCNA reduce stent induced stenosis in a porcine coronary model. Am J of Card

14. Frimerman A, Eigler N, Fishbein MC, Ren M, Makkar R, Litvack F: In vivo adenovirus mediated gene transfer in a porcine coronary stent model: a dose response, toxicity study. Am J of Card

15. Makkar R, Whiting JS, Li AN, Cordero H, Honda H, Frimerman A, Litvack F, Eigler N: A beta emitting liquid isotope filled balloon markedly inhibits restenosis in stented porcine coronary arteries. JACC 1998;31(2):870-2, 350A.

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16. Makkar R, Eigler NL, Goff B, Fry ETA, Barr L, D’Haem CM, Fischell TA, Litvack F: Primary reperfusion in acute myocardial infarction with ReoPro and heparin: interim results of ReoMI pilot study. JACC 1998;31(2):1028-112, 94A.

17. Makkar R, Honda H, Li A, Cordero H, Sebastian M, Chrnomorsky A, Whiting J, Litvack F, Eigler N: Brachytherapy with ß-emitting rhenium-188 balloon following stent implantation inhibits restenosis. (submitted to AHA)

18. Makkar R, Whiting J, Honda H, Li A, Cordero H, Chernomorsky A,Litvack F, Eigler N: Inhibition of stent restenosis by ß-emitting rhenium-188 balloon is dose-dependent and injury-independent. (submitted to AHA)

19. Makkar R, Shah PK, Terhakopian A, Cercek B, Fishbein MC, Kaul S: Intrapericardial delivery of a nitric oxide donor inhibits in-stent stenosis in porcine coronary arteries. (submitted to AHA)

20. Sebastian M, Honda H, Makkar R, Cordero H, Robbins J, Barber J, Eigler N, Litvack F: Local delivery of chimeric DNA:RNA ribozymes targeting PCNA with the Cordis Crescendo catheter inhibits in-stent restenosis in a porcine model. J ACC 1999;33(2):834-6, 60A.

21. Frimerman A, Honda H, Makkar R, Eigler N, Welch P, Barber J, Litvack F: Ribozymes to conserved human-porcine PCNA reduce in-stent restenosis in a porcine moel. JACC 1998;31(2):1063-105,145A.

22. Hausleiter J, Li AN, Abbey C, Makkar R, Whiting JS, Eigler NL. Identification of the target tissue by comparison of studies with widely fifferent dose/depth functions. Syllabus of Cardiovascular Radiation Therapy III:33,1999.

23. Sebastian M, Honda H, Robbins J, Hausleiter J, Makkar R, Eigler N, Litvack F. Catheter-based delivery of ribozymes targeting PCNA mRNA after stenting reduces neointimal hyperplasia in a porcine model (accepted for presentation at European Society of Cardiology XXIst Congress, Barcelona 1999).

24. Honda H,Hausleiter J, Makkar R, Whiting JS, Eigler NL. Edge stenosis after “Low Dose” radiation therapy using a Re-188 liquid-filled balloon system. Syllabus for Cardiovascular Radiation Therapy III:30,1999.

25. Hausleiter J, Li A, Makkar R, Honda H, Whiting JS, Eigler N. “The Effect of Low Dose Radiation Therapy on Edge Stenosis Formation in the Pig Model.” 11th Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Washington, DC, September 1999.

26. Hausleiter J, Li A, Abbey C, Makkar R, Honda H, Whiting JS, Eigler N. “New Dose Effectiveness Model Intracoronary Brachytherapy Predicts External Beam Irradiation Results in the Pig Model”. 11th Transcatheter Cardiovacsular therapeutics (TCT) symposium, Washington, DC, September 1999.

27. Hausleiter J, LI A, Abbey C, Makkar R, Sebastian M, Honda H, Whiting JS, Eigler N. “New Dose-Effectiveness Model for Intracoronary Brachytherapy Predicts External Beam Irradiation Results in the Pig Model.” AM J Cardiol, 84, Suppl.6a,2P,1999.

28. Hausleiter J, Li A, Makkar R, Whiting J, Eigler N: Localization of target tissue and the minimum effective dose in intracoronary radiation therapy. JACC 1999;3(2):1070-59, 44A.

29. Frimerman A, Welch PJ, Jin X, Eigler N, Yei s, Forrester J, Honda H, Makkar R, Barber J, Litvack F. Chimeric DNA-RNA hammerhead ribozyme to PCNA reduces stent induced stenosis in a porcine coronary model. Circulation 1999;99:697-703.

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30. Kaul S, Makkar RR, Terhakopian A, Sinaii N, Shah PK: Pharmacokinetic profile of intrapericardial administration of NO donors critically modulates the vascular response to injury. JACC 1999;33(2):1190-134, 88A.

31. Honda H, Sebastian M, Robbins J, Alspaugh E, Barber J, Makkar R, Eigler N, Litvack F: Catheter-based local delivery of ribozymes targeting PCNA mRNA administered post stenting reduces in-stent neointimal hyperplasia in pig coronary arteries. Circulation 2000;100(18):4460.

32. Honda H, Makkar R, Li A, Sebastian M, Fishbein MC, Whiting J, Litvack F, Eigler N: Experimental stent edge stenosis after intravascular radiation therapy. Circulation 2000;100(18):1155.

33. Aboul-Enein FA, Kar S, Hayes SW, Makkar R, Lewin HC, Friedman JD, Berman DS: Influence of angiographic collaterals on myocardial perfusion in patients with chronic total occlusion of a single coronary artery and no history of myocardial infarction. JACC 37(2) Supplement A, 882-5, 2001.

34. Finkelstein A, Hausleiter J, Takizawak, Bergman J, Fishbein M, Eigler N, Shah PK, Rajavashisth T, Makkar R: Intracoronary brachytherapy increases vascular tissue factor expression in the porcine injury model: a possible explanation for delayed thrombosis? Circulation 2001;104(17):2588.

35. Hausleiter J, Li A, Takizawa K, Finkelstein A, Makkar R, Eigler N, and Whiting J.S. Discordant intracoronary brachytherapy results in adult mini-pig restenosis models: How useful are these models for predicting safety and efficacy in man? JACC 37(2) Supplement A 29A, 2001.

36. Takizawa K, Qayyum MS, Frantzen M, MacLellan R, Lill M, Fishbein MC, Makkar R: Feasibility of an intracoronary injection method for cell transplantation in a porcine model. TCT Meeting, September, 2001.

37. Qayyum MS, Takizawa K, Frantzen M, MacLellan R, Lill M, Fishbein MC, Miyamoto T, Makkar R: Mesenchymal stem cell therapy prevents deterioration of left ventricular function in a porcine myocardial infarction model. Supplement to Journal of the American College of Cardiology, March 6, 2002, Vol. 39, Issue 5, Suppl. A:169A.

38. Takizawa K, Hausleiter J, Finkelstein A, Bergman J, Rukshin V, Tsang V, Kar S, Eigler N, Forrester J, Makkar R: Efficacy of cilostazol in stent thrombosis and restenosis in a porcine model. Submitted to ACC 2002

39. Takizawa K, Qayyum M, Frantzen M, MacLellan R, Lill M, Fishbein MC, Miyamoto T, Makkar R: Feasibility of an intracoronary injection method for cell transplantation in a porcine model. Submitted to ACC 2002.

40. Pak HN, Qayyum M, Lai AC, Kim DT, Hamabe A, Miyauchi Y, Lill MC, Takizawa K, Fishbein MC, Sharifi BG, Chen PS, Makkar R: Mesenchymal stem cell injection induces cardiac nerve sprouting and tenascin expression in a swine model of myocardial infarction. Supplement to Journal of the American College of Cardiology, March 6, 2002, Vol. 39, Issue 5, Suppl. A:445A.

41. Price MJ, Frantzen M, Martin BJ, McClean D, Kar S, Lee S, Shah PK, Lill M, Makkar R: Intravenous infusion of allogenic mesenchymal stem cells reduces left ventricular remodeling in a porcine model of acute myocardial infarction. SCAI 2003.

42. Makkar RR, Price M, Lill M, Takizawa K, Frantzen M, Fishbein M, Kar S, Kleisli T, Zheng J, Sharifi B, Qayyum M: Multilineage differentiation of transplanted allogenic

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mesenchymal stem cells injected in a porcine model of recent myocardial infarction improves left ventricular function. Circulation 2002;106(19), 158.

43. McClean D, Finkelstein A, Kar S, Takizawa K, Honda T, Baek N, Park K, Fishbein MC, Makkar R, Litvack F, Eigler N: Local drug delivery using a stent with programmable pharmacokinetics in vitro and in porcine coronary arteries. Circulation 2002;106(19), 2225.

44. Honda H, Kar S, Honda T, Takizawa K, Meguro T, Fishbein M, Makkar R, Eigler N, Litvack F. Everolimus Eluting Stents significantly inhibit neointimal hyperplasia in experimental pig coronary model. Am J Cardiol 2002; 90 (suppl 6A): 73H.

45. Kar S, Naqvi T, Price M, Aragon J, Makkar R, Eigler N. Use of Intracardiac Echocardiography for Guiding Device Closure of Interatrial Communications. The J of Heart Disease (Abstract Issue) 2003;3:31

46. Kar S, McClean D, Aragon J, Makkar R, Litvack F, Whiting J, Eigler N. Implantable Physiologic Optimized Dosimeter for Treating Advanced Congestive Heart Failure. The J of Heart Disease (Abstract Issue) 2003, 3:45.

47. Kar S, McClean D, Aragon J, Makkar R, Litvack F, Whiting J, Eigler N. Cedars-Sinai Medical Center, Implantable Left Atrial Physiologic Optimized Dosimeter for Treating Advanced Congestive Heart Failure. Am J Cardiol 2003; 92 (SuppA): 199L.

48. Kar S, Price M, McClean D, Naqvi T, Aragon J, Kotler H, Makkar R, Eigler N. The use of Intracardiac Echocardiography in help guiding Closure of Interatrial Communications. Am J Cardiol 2003; 92 (Suppl A):13L.

49. Lee MS, Makkar RR, Rametta S, Singh V, Levitt H, Khan A, Wilentz J. New heparin dosing regimen for diabetics undergoing percutaneous coronary intervention (abstract). Society of Cardiovascular Angiography and Interventions 2004.

50. Lee MS, Rametta S, Wilentz J, Singh V, Levitt H, Makkar RR. Elevated Creatine Kinase on Admission Is Associated with an Increased In-Hospital Mortality in Patients Treated with Primary and Rescue Percutaneous Coronary Intervention in Acute Myocardial Infarction (abstract). Society of Cardiovascular Angiography and Interventions 2004.

51. Lee MS, Makkar RR, Singh V, Rametta S, Valania G, Wilentz J. Preprocedural administration of aminophylline does not prevent AngioJet rheolytic thrombectomy-induced bradyarrhythmias (abstract). Society of Cardiovascular Angiography and Interventions 2004.

52. Lee MS, Shah A, Dang N, Bobo D, Berman D, Friedman J, Aragon J, Makkar RR. The coronary sinus is a potential target for percutaneous mitral valve repair as it dilates and is outwardly displaced in patients with mitral regurgitation. American College of Cardiology 2005. JACC

53. Lee MS, Shah AP, Jamali A, Kar S, Dohad S, Aragon J, Makkar RR. Drug-eluting stenting is superior to bare-metal stenting in saphenous vein grafts (abstract). TCT Asia Pacific 2005.

54. Lee MS, Shah AP, Friedman J, Dang N, Bobo D, Fariabi S, Kar S, Aragon J, Caraang C, Berman D, Makkar RR. Characterization of the coronary venous system with contrast-enhanced electron beam computed tomography (abstract). TCT Asia Pacific 2005.

55. Lee MS, Shah AP, Friedman J, Dang N, Bobo D, Fariabi S, Kar S, Aragon J, Caraang C, Berman D, Makkar RR. Contrast-Enhanced Electron Beam Computed

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Tomography Provides Detailed Characterization of the Coronary Venous System (abstract). Society of Cardiovascular Angiography and Interventions 2005.

56. Tarun Chakravarty, Mamta Buch, Anthony J. White, Hursh Naik, Niraj Doctor, Jay Schapira, Saibal Kar, James S. Forrester, Robert E. Weiss, Raj Makkar:Incidence, Clinical Characteristics and Implications of Coronary Stent Fracture: A Meta-analysis of 5321 patients. AHA Scientific Sessions 2009. Oral Abstract.

57. Tarun Chakravarty, Mamta Buch, Hursh Naik, James S. Forrester, Niraj Doctor, James M. Mirocha, Raj Makkar: SYNTAX Score Predicts Major Adverse Cardiovascular and Cerebrovascular Event (MACCE)-free Survival, But Not Overall Survival, In Unprotected Left Main Coronary Artery (ULMCA) Patients Undergoing Percutaneous Coronary Revascularization (PCI): 3-Year Follow-up Analysis. AHA Scientific Sessions 2009.

58. Tarun Chakravarty, Satoshi Matsushita, John Terrovitis, James S. Forrester, Taosheng Li, Konstantinos Malliaras, Anthony J. White, Prabhav Anand, Darryl Davis, Yigiang Zhang, Rachel R. Smith, Niraj Doctor, Eduardo Marbán, Raj Makkar. Thymosin beta-4 enhances cardiosphere-derived cardiac stem cell CDC)-mediated cardioprotection by promoting CDC migration and angiogenesis via Akt phosphorylation. AHA Scientific Sessions 2009.

59. Shuo-Tsan Lee; Anthony J White; Satoshi Matsushita; Tao-Sheng Li; Konstantinos Malliaras; Supurna Chowdhury; Adrian Glenn; Hao Zeng; Yiqiang Zhang; Ioannis Terrovitis; Sinan Simsir; Raj Makkar; Eduardo Marbán. Direct Intramyocardial Injection of Autologous Cardiosphere-Derived Cells Yields Consistent Engraftment and Improves Cardiac Function in a Porcine Model of Ischemic Cardiomyopathy. Circulation. 2009;120:S898. 60.Tarun Chakravarty, Ryan P Morrissey, Brett Wertman, Jesse Naghi, Stanley Chou, Pavel Goykhman, Sean Hirota, Niraj Doctor, James M Mirocha, James S Forrester, Raj Makkar. Comparison of Drug-eluting Stents to Bare Metal Stents for Saphenous Vein Graft Stenosis: Longest Available Follow-up Analysis. Circulation. 2010;122:A19031.61. Tarun Chakravarty, Ryan P Morrissey, Anthony J White, Niraj Doctor, Gregory Fontana, Alfredo Trento, Suhail Dohad, James M Mirocha, James S Forrester, Raj Makkar. Percutaneous Coronary Intervention (PCI) is Equivalent to Coronary Artery Bypass Grafting (CABG) for Unprotected Left Main Coronary Artery Disease: 5 year Follow-up Analysis. Circulation. 2010;122:A18982.62. Niraj Doctor, Hasan Jilaihawi, Kashif Mohammad, Tarun Chakravarty, Raj Makkar: Low Incidence of Femoral Vascular Complications with Primary and Repeat Perclose Pre-closing for Balloon Aortic Valvuloplasty: Data from a Large PARTNER- contemporary Single Center Series. J. Am. Coll. Cardiol., April 5, 2011; 57: E1347. 63.Konstantinos Malliaras; Satoshi Matsushita; Anthony J. White; Shuo-Tsan Lee; Charles Steenbergen; Yiqiang Zhang; Tao-Sheng Li; John Terrovitis; Sinan Simsir; Raj Makkar; Eduardo Maran. Intramyocardial Injection of Autologous Cardiospheres or Cardiosphere-Derived Cells Preserves Function and Minimizes Adverse Ventricular Remodeling in Pigs With Heart Failure Post-Myocardial Infarction. Circulation. 2010;122:A19030.64.Hideaki Kanazawa, Konstantinos Malliaras, Kristine Yee, Eleni Tseliou, Linda

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Marban, Raj Makkar, and Eduardo Marban. Comparison of Cardiac Engraftment With Two Catheter-Based Delivery Methods: Catheter-Mediated Intramyocardial Delivery Outperforms Intracoronary Delivery of Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy. Circulation. 2011;124:A16466.65.Babak Azarbal, Janet Wei, Sarabjeet Singh, Jesse Currier, Jignesh Patel, Antoine Hage, Raj Makkar, and Jon Kobashigawa. Frequency of Coronary Artery Fistulae and Extracardiac Neovascularization After Orthotopic Heart Transplantation. Circulation. 2011;124:A1406366.Ke Cheng, Agnieszka Blusztajin, Deliang Shen, Rachel R Smith, Raj Makkar, Eduardo Marban, and Linda Marban. Enhanced Engraftment and Therapeutic Benefit of Human Cardiosphere-Derived Cells Delivered in an In Situ Polymerizable Hydrogel. Circulation. 2011;124:A17267.67.Asim M Rafique, Hasan Jilaihawi, Niraj Doctor, Chakravarty Tarun, Mohammad Kashif, Doumanian Aik, Stegic Jasminka, Lauren Contreras, Gheorghiu Mitch, Nakamura Mamoo, Gregory Fontana, Wen Cheng, and Raj R Makkar. Prognostic Value of B-type Natriuretic Peptide in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. Circulation. 2012;126:A1822268.Kenji Harada, Jun Tanaka, Hasan Jilaihawi, Jasminka Stegic, Niraj Doctor, Mohammad Kashif, Mamoo Nakamura, Tarun Chakravarty, Raj Makkar, and Shiota Takahiro. Changes in Left Ventricular Diastolic and Left Atrial Function One Month After Transcatheter and Surgical Aortic Valve Replacement in Severe Aortic Valve Stenosis. Circulation. 2012;126:A9117.69.Niraj S Doctor, Hasan S Jilaihawi, Chakravarty Tarun, Rafiq Asim, Lauren A Contreras, Stegic Jasminka, Mohammad Kashif, Doumanian Aik, Gheorghiu Mitch, Nakamura Mamoo, Gerald Friede, and Raj Makkar. Prevalence of Neoplastic and Non-Neoplastic Incidental Findings as Detected by Computed Tomography in Severe Aortic Stenosis: Single Center PARTNER Trial Data. Circulation. 2012;126:A19458.70.Asim M Rafique, Hasan Jilaihawi, Niraj Doctor, Chakravarty Tarun, Mohammad Kashif, Doumanian Aik, Stegic Jasminka, Lauren Contreras, Gheorghiu Mitch, Nakamura Mamoo, Gregory Fontana, Wen Cheng, and Raj R Makkar. Prognostic Value of Elevated Pulmonary Artery Pressure in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. Circulation. 2012;126:A17015.71.Hideaki Kanazawa, Konstantinos Malliaras, Kristine Yee, James Dawkins, Eleni Tseliou, Linda Marban, Raj Makkar, and Eduardo Marban. Allogeneic Cardiosphere- Derived Cells Reduce Infarct Size and Attenuate No-Reflow when Administered in the Infarct-Related Artery after Reperfusion in Pigs with Acute Myocardial Infarction. Circulation. 2012;126:A13641.72.Konstantinos Malliaras, Ke Cheng, Rachel Smith, Adam Mendizabal, Gary Gerstenblith, Linda Marban, Raj Makkar, and Eduardo Marban. Intracoronary Cardiosphere-Derived Cells for Heart Regeneration after Myocardial Infarction: Determinants of Regenerative Efficacy in the Final 1-Year Results of the CADUCEUS Trial. Circulation. 2012;126:A14781.73.Ke Cheng, Deliang Shen, Baiming Sun, Konstantinos Malliaras, Rachel Smith, Supurna Chowdhury, Doan Tran Duong, Raj Makkar, and Eduardo Marban. Irrelevance of C-Kit-Positive Subpopulation to the Therapeutic Benefit of Human Cardiosphere-Derived Cells. Circulation. 2012;126:A13259.

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74.Mamoo Nakamura, Tarun Chakravarty, Hasan Jilaihawi, Niraj Doctor, Suhail Dohad, Greg Fontana, Wen Cheng, Raj Makkar. Complete Percutaneous Approach For Arterial Access And Closure For Device Deployment In The Transfemoral Transcatheter Aortic Valve Replacement - A Comparison With Surgical Cut-down. J Am Coll Cardiol. 2012;60(17_S):. doi:10.1016/j.jacc.2012.08.448.75.Mamoo Nakamura, Tarun Chakravarty, Hasan Jilaihawi, Niraj Doctor, Suhail Dohad, Greg Fontana, Wen Cheng, Raj Makkar. Major Vascular Complication And Its Management After Complete Percutaneous Arterial Access And Closure In Transfemoral Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2012;60(17_S):. doi:10.1016/j.jacc.2012.08.449.76.Asma Hussaini, Wen Loong Yeow, Takashi Matsumoto, Mamoo Nakamura, Hassan Jlaihawi, Raj Makkar, Saibal Kar. Large 22 to 24Fr femoral vein hemostasis with a subcutaneous stitch or a double Perclose closure is effective and safe. J Am Coll Cardiol. 2012;60(17_S):. doi:10.1016/j.jacc.2012.08.451.77. Raj Makkar, Andrew Hamer, Eduardo Marban, Fraces Kivel, Jay H. Traverse, Katherine Beattie, Linda Marban, Rachel Smith, Richard Schatz, Timothy D. Henry. TCT 152: ALLogeneic Heart STem Cells To Achieve Myocardial Regeneration (ALLSTAR): The Six Month Phase I Safety Results.78 Rakes M. Suri, Augusto Pichard, Craig Smith, Danny Dvir, Darshan Doshi, John Webb, Jonathon Leipsic, Kevin Greason, Lars Svensson, Lowell Satler, Martin Leon, Michael Mack, Raj Makkar, Todd Dewey Vinod Thourani. : TCT 688: One-Year Results of Transcatheter Aortic Valve Therapy for Failed Surgical Bioprosthese PARTNER II Valve-in-Valve Registry.79. Babak Azarbal, Chang David, Fardad Esmailian, Francisco Arabia, Jaime Moriguchi, Jon Kobashigawa, Raj Makkar. TCT 70: No Survival Benefit with se of Intra- Aortic Balloon Pump in Extracorporeal Membrane Oxygenation: A Pooled Experience of 1,517 Patients.80. Tarun Chakravarty, Hasan Al-Jilaihawi, Mamoo Nakamura, Raj Makkar, Wen Cheng, Yigal Abramowitz. TCT 1330: Percutaneous Approach for Sever Paravalvular and Central Aortic Regurgitation due to Bioprosthetic Aortic Valve Degeneration: Staged Transcatheter Paravalvular Leak Closure followed by valve-in- valve-out.81. Yigal Abramowitz, Hasan Al-Jilaihawi, Mamoo Nakamura, Raj Makkar, Tarun Chakravarty, Wen Cheng. TCT 1376: Transcatheter Aortic Valve Replacement in a Patient with Sever Aortic Regurgitation.82. Tarun Chakravarty, Amit Noheria, Andrea Hutter, Andreas Raeck, Francesco Bedogni, Hasan Al-Jilaihawi, Luca Testa, Marco Barbanti, Martin Leon, Martyn Thomas, Muhammed Khawaja, Raj Makkar, Stefan Toggweiler, Webb John, Wen Cheng, Yigal Abromowitz, Eric Van Belle. TCT 706: A Collaborative Meta-analysis of the Impact of Mitral Regurgitation on Outcomes after Transcatheter Aortic Valve Replacement: 8 Studies Involving 8919 Patients.83. Boris Arbit, Babak Azarbal, Christopher Vanichsarn, David Chang, Jignesh Patel, Jon Kobashigawa, Raj Makkar. TCT 100: Long Term Clinical and Angiographic Outcomes with Everolimus-Eluting Stents for Cardiac Allograft Vasculopathy.84. Vikash Singh, Ankit, Chothani, Apurva Badheka, Badal Thakkar, Carlos Alfonso, Chad Kliger, Cindy Grines, Conrad Macon, Ghanshyambhai Savani, Jay Patel, John

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Forrest, Mauricio Cohen, Michael Cleman, Neil Patel, Nilay Patel, Nileshkumar Patel, Raj Makkar, Shantanu Solanki, Sohilkumar Manavar, Theodore Schreiber, Vinaykumar Panchal, William O’Neill. TCT 786: In-Hospital Outcomes of Balloon Aortic Valvuloplasty and Percutaneous Coronary Intervention During the Same Hospitalization in the US. 85. Tarun Chakravarty, Hasan Al-Jilaihawi, Mamoo Nakamura, Raj Makkar, Wen Cheng, Yigal Abramowitz. TCT 1322: First Report of Transapical Approach for Left Ventricular Pseudoaneurysm Closure after Transcatheter Aortic Valve Replacement. 86. Hasan Al-Jilaihawi, Mamoo Nakamura, Raj Makkar, Wen Cheng. TCT 1337: Left main protection and stenting during a Valve-in-valve Core-valve Deployment in a Previously Replaced Aortic Valve with a Mitroflow Valve.87. Asim Rafique, Hasan Jilaihawi, Tarun Chakravarty, Niraj Doctor, Wen Cheng, Mohammad Kashif, Raj Makkar. Influence of Chronic Kidney Disease on Left Ventricular Remodeling and Outcomes in Patients Undergoing Trans-Catheter or Surgical Aortic Valve Replacement. ACC 2015.88. Mamoo Nakamura, Abhijeet Dhoble, Jorge Castellanos, Hasan Jilaihawi, Wen Cheng, Raj Makkar. Intracardiac Echocardiography Guided Transfemoral Transcatheter Aortic Valve Replacement Without Endotracheal Intubation. ACC 2015.89. Yigal Abramowitz, Hasan Jilaihawi, Tarun Chakravarty, Mohammad Kashif, Yoshio Maeno, Yoshio Kazuno, Nobuyuki Takahashi, Mamoo Nakamura, Wen Cheng, Raj Makkar. Balloon-Expandable Transcatheter Aortic Valve Replacement in Patients with Extreme Aortic Valve Calcification. ACC 2015.90. Jigar Patel , Babak Hariri , Geeteshwar Mangat , Tarun Chakravarty , Yigal Abramowitz , Yoshio Kazuno ,Jasminka Stegic , Tracy Salseth , Stephanie Khouw , Mitch Gheorghiu , Hasan Jilaihawi , Wen Cheng , Raj Makkar. First Report of Successful Management of Left Main Occlusion during TAVR with Snaring of the CoreValve. TCT 2015 poster.91. Babak Hariri , Jigar Patel , Geeteshwar Mangat , Tarun Chakravarty , Mitch Gheorghiu , Jasminka Stegic , Tracy Salseth , Stephanie Khouw , George W Matar , Mohammad Kashif , Mamoo Nakamura , Hasan Jilaihawi , Wen Cheng , Raj Makkar. Right Coronary Artery Occlusion Caused By Pannus or Possible Thrombus During Transcatheter Valve In Transcatheter Valve Deployment: First Report. TCT 2015 poster.92. Daubert M, Weissman N, Hahn R, Pibarot P, Parvataneni R, Mack M, Kapadia S, Siegel R, Svensson LG, Kodali S, Szeto WY, Makkar R, Leon M, Douglas PS. The Long-term Hemodynamic Performance of Transcatheter Aortic Valve Replacement: A Report from the PARTNER I Trial. TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.14093. Takahashi N, Kazuno Y, Maeno Y, Kashif M, Kawamori H, Okuyama K, Abramowitz Y, Chakravarty T, Nakamura M, Cheng W, Makkar R, Jilaihawi H. Impact of Ultra-Low Contrast Computed Tomography Compared to Three- Dimensional Transesopageal Echocardiography for Transcatheter Aortic Valve Replacement planning. TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.34994. Vanichsarn CT, Arbit B, Cheng R, Aintablian T, Makkar R, Kobashigawa J, Azarbal

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B. Four-Year Clinical and Angiographic Outcomes of Percutaneous Coronary Intervention with Everolimus-Eluting Stents for the Treatment of Cardiac Allograft Vasculopathy. TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.46895. Abramowitz Y, Jilaihawi H, Chakravarty T, Kashif M, Kazuno Y, Maeno Y, Takahasi N, Kawamori H, Sharma RP, Cox J, Cheng W, Makkar R. Balloon- Expandable Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Mild Aortic Valve Calcification. TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.64896. Chakravarty T, Sharma RP, Abramoqitz Y, Kapadia S, Latib A, Jilaihawi H, Poddar KL, Giustin G, Ribeiro HB, Tchetche D, Monteil B, Testa L, Tarantini G, Facchin M, Lefevre T, Lindman BR, Hariri B, Patel J, Takahashi N, Matar GW, Mirocha J, Cheng W, Tuzcu EM, Sievert H, Rodes-Cabau J, Colombo A, Finkelstein A, Fajadet J, Makkar R. Outcomes in Patients with Transcatheter Aortic Valve Replacement and Left Main Stent: The multicenter, multinational TAVR-LM Registry. TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.67197. Santos MS, Duncan A, Webb J, Bapat V, Lefevre T, Attizzani GF, Hernandez-Garcia JM, Lemos PA, Welsh RC, Ladanza A, Salizzoni S, Agirofoglio M, Presbitero P, Bruschi G, Himbert D, Makkar R, Salemi A, Teles RC, Marzocchi A, Hellig F, Gafoor S, Chakravarty T, Finkelstein A, Kornowski R, Dvir D. Stentless vs. Stented Aortic Valve-in-Valve Implantation: Insights from the Valve-in-Valve International Data Registry (VIVID). TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.69698. Maeno Y, Kazuno Y, Abramowitz Y, Kawamori H, Takahashi N, Kashif M, Chakravarty T, Nakamara M, Cheng W, Makkar R, Jilaihawi H. Aggressive oversizing of balloon-expandable transcatheter aortic valve replacement: predictor of para valvular leak with severe aortic valvar complex calcification. TCT 2015. J Am Coll Cardiol. 2015; 66(15_S) doi: 10.1016/j.jacc.2015.08.700

Edited 10/24/16

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