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CAM PAK 11-6-2014 Prof Adi Hidayat

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    Pengobatan komplementer danalternatif (Complementary and

    Alternative Medicine)

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    Sasaran belajar

    Mampu mendefinisikan pengobatan

    komplementer dan alternatif

    (PKA)/{complementary and alternativemedicine (CAM)} dalam hubungannya

    dengan pengobatan konvensional

    Mampu mereview penemuan danpenelitian mutakhir tentang PKA/CAM

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    Sasaran belajar

    Mampu berkomunikasi dan menasihatkan

    pasien tentang PKA/CAM baik evidence-based research maupun patient values

    and preferences.

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    Definisi PKA/CAM Setiap tindakan baik yang tidak diajarkan di fakultas

    kedokteran maupun tidak tersedia di rumah sakit(Interventions neither taught in medical school, norgenerally available in hospital) (1)

    Pengobatan yang berada diluar model biomedisBarat tentang penyakit, diagnosis dan pengobatan(healing therapies that typically fall outside theWestern biomedical model of disease, diagnosis,

    and treatment) (2)

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    Definisi PKA/CAM

    The World Health Organisation : "all

    forms of health care which usually lie

    outside the official health sector (3)

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    Apakah pengobatankomplementer berbeda dengan

    pengobatan alternatif ? Ya (4)

    PK digunakan bersama pengobatan

    konvensional. Misal aromatherapy untukmengurangi rasa tidak enak pasien setelah operasi

    PA digunakan untuk menggantikan pengobatan

    konvensional, misal diet khusus unuk pengobatankanker dan bukan pembedahan radiasi atau

    kemoterapi

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    Apakah kedokteran integrasi(integrative medicine)?

    Integrative medicine combines treatments

    from conventional medicine and CAM forwhich there is some high-quality evidence

    of safety and effectiveness.

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    Lima tipe mayor dari PKA (4) Whole Medical Systems,traditional Chinese

    medicine, homeopathy, naturopathy, botanical,acupuncture, moxibustion and Ayurveda

    Mind-body interventions, meditation, prayer,mental healing, art, music, or dance.

    Biologically-based treatments substancesfound in nature, herbs, foods, and vitamins. Some

    examples dietary supplements, herbal products,unproven therapies (shark cartilage to treatcancer),lifestyle (exercise,relaxation).

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    Tipe mayor dari PAK Manipulative and body-based methods

    manipulation and/or movement of one ormore parts of the body, chiropractic orosteopathic, and massage.

    Energy therapies two types: i) Biofieldtherapiesqi gong, Reiki, and TherapeuticTouch, ii) Bioelectromagnetic-based

    therapies, pulsed fields, magnetic fields, oralternating-current or direct-current fields.

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    Jenis PKA di masyarakatAcupuncture Imagery

    Aromatherapy Magnets

    Biofeedback Massage

    Chiropractic Prayer

    Diets ReflexologyExercise Relaxation

    Folk remedies Self-help/support groups

    Herbal/botanical therapy Spiritual healing (by others)

    Homeopathy Vitamins

    Hypnosis Yoga

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    Siapa pengguna PKA?

    1997, 47% penduduk US menggunakan PAK(5)

    2002, 75%of U.S. adults reported use of

    CAM in lifetime and 62%in past 12 months(when prayer included) (6)

    Survei Sosial Ekonomi Nasional tahun 2001,

    31,7% menggunakan obat tradisional, dan

    9,8% pengobatan tradisional (7)

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    Mengapa masayarakatmenggunakan PKA ?

    WHO 80% masyarakat menggunakan PKA

    Desire for health and wellness

    Prevention Cancer- recent estimate 83% (8)

    Pain : -Musculoskeletal pain

    Back and neck pain

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    Why do people use CAM?

    Desire for health and wellness (1)

    Prevention

    Cancer- recent estimate 83% (2)

    Pain

    Musculoskeletal pain

    Back and neck pain

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    What do CAM users want?

    Empowerment in medical interactions

    Chance to share their own views about healthand healing

    Health provider who will spend time with them

    Someone who will answer their questions

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    Evidence-based Medicine (EBM)and CAM

    EBM aims to integrate

    best research evidence clinical expertise

    patient values

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    EBM and CAM

    While some scientific evidence exists

    regarding some CAM therapies, for most

    there are key questionsthat are yet to be

    answered through well-designed scientific

    studiesquestions such as whether they are

    safe and whether they workfor the diseasesor medical conditions for which they are used.

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    Where does this leave us?

    CAM interventions generally

    are low cost

    are low risk

    are free of serious side effects

    AND

    are widely used.

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    CAM: evidence and research

    Glucosamine/Chondroitin Arthritis

    Echinacea for the Prevention and

    Treatment of Colds

    St John's wort) in major depressive disorder

    Acupuncture for Osteoarthritis

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    Glucosamine/Chondroitin Arthritis

    Intervention Trial (GAIT) Study Results(9)

    Supplement combination of glucosamine

    plus chondroitin sulfate did not provide

    significant relief from osteoarthritis painamong all participants.

    However, a smaller study participants with

    moderate-to-severe pain showed significantrelief with the combined supplements.

    CAM: evidence and research

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    CAM: evidence and research Echinacea for the Prevention and Treatment of

    Colds in Adults: Research Results and

    Implications for Future Studies (10)

    437 healthy adult volunteers were assigned at random

    to receive one of the three E. angustifoliapreparationsor a placebo. They received in two phases: a

    "prophylaxis" and a treatment phase. The prophylaxis

    phase lasted 7 days. On the 7 day, the already treated

    subjects were exposed to a nasal spray containing avirus that induces signs and symptoms of a cold in

    about 2 days.

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    CAM: evidence and research Volunteers were isolated for 5 days, tested them,

    appearance and severity of cold signs and

    symptoms

    None of the three preparations of E. angustifoliaat

    the 900 mg per day dose had significant effects onthe severity or duration of symptoms among those

    who developed colds. However, critics of this study

    believe the dose of E. angustifoliaused was too

    low.

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    CAM: evidence and research Effect of Hypericum perforatum (St John's wort) in

    major depressive disorder: a randomized controlledtrial. (11)

    OBJECTIVE: To test the efficacy and safety of awell-characterized H perforatum extract (LI-160) in

    major depressive disorder.

    DESIGN AND SETTING: Double-blind,randomized, placebo-controlled trial conducted in12 academic and community psychiatric researchclinics in the United States.

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    CAM: evidence and research PARTICIPANTS: Adult outpatients (n = 340)

    recruited with major depression and a baselinetotal score on the Hamilton Depression Scale(HAM-D) of at least 20.

    CONCLUSION: This study fails support theefficacy of H perforatum in moderately severemajor depression. The result may be due to lowassay sensitivity of the trial, but the completeabsence of trends suggestive of efficacy for H

    perforatum is noteworthy (perlu diperhatikan).

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    CAM: evidence and research

    Acupuncture for peripheral joint osteoarthritis Asystematic review and meta-analysis (12)

    Objective. To evaluate the evidence for the

    effectiveness of acupuncture in peripheral joint

    osteoarthritis (OA). Methods. Systematic searches were conducted on

    Medline, Embase, AMED, Cochrane Library,

    CINAHL, British Nursing Index, PsychINFO and

    CAMPAIN

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    CAM: evidence and research

    Results. Thirty-one possibly relevant studies wereidentified and 18 RCTs were included.

    Conclusions. Sham (pura-pura)-controlled RCTs

    suggest effects of acupuncture for pain control in

    patients with peripheral joint OA. Considering itsfavourable safety profile acupuncture seems an

    option worthy of consideration particularly for knee

    OA.

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    What about communication?

    Between 40 and 70% of CAM users do notdisc losetheir use to their physician.

    WHY?

    Patients usually say that they do not report

    because they are not asked.

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    Why does this matter?

    The substantial overlap between use ofprescription medications and herbal

    supplements raises concerns about unintended

    interactions.

    Patient use of CAM is often a clue to values

    and preferencesthat need to be

    acknowledged.

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    How can we communicate?

    1. Always ask!What else are you doing for yourhealth?

    2. Be open and nonjudgmental.

    3. Consider patient preferences and values.

    4. Be honestabout your lack of knowledge

    5. Sadar adanya efek samping & kontraindikasi

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    Efek samping/kontraindikasi (13)

    Echinacea : autoimmune rseponse, tidak bolehdiberikan AIDS, TBC, multiple sclerosis

    St Johns wort : efek samping fotosensitif akibat

    komponen hipericin

    Ginkgo biloba ; efek inhibitor on platelet-activatingfactor, avoid pasien bleeding disorders,

    thrombocytopenia, bilateral subdural hematoma

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    Daftar Pustaka

    1. Eisenberg DM, Kessler RC, Foster C.

    Unconventional medicine in the United States :

    prevalence, cost and patterns of use. N Engl J

    Med 1993;328:246-52.

    2. Drivdahl CE, Miser WF: The use of alternative

    healthcare by a family practice population. J

    Am Board Fam Prac1998, 11:193-9.

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    Daftar Pustaka

    3. Gureje O, Von Korff M, Gregory SE, Richard G.

    Persistent pain well-being. A World Health

    Organization study in primary care. JAMA1998,280:147-51.

    4. National Center for Complementary and Alternative

    Medicine (NCCAM). What Is CAM? Available at :

    http://nccam.nih.gov/health/whatiscam/. AccessedNovember 22, 2007.

    http://nccam.nih.gov/health/whatiscam/http://nccam.nih.gov/health/whatiscam/
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    Daftar Pustaka

    5. Eisenberg DM, Davies RF, Ettnier SL. Trends in

    alternative medicine uses in the United States

    1990-97. JAMA 1998;280:1569-75.6. Barnes P, Powell-Griner E, McFann K, Nahin R.

    CDC Advance Data Report #343. Complementary

    and Alternative Medicine Use Among Adults:

    United States, 2002.Atlanta, 2004.

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    Daftar Pustaka

    7. Departemen Kesehatan R.I. Wajib Daftar bagiPengobatan Tradisional. Available at :http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=434. Accessed

    November,22,20078. National Center for Complementary and

    Alternative Medicine (NCCAM). The Use ofComplementary and Alternative Medicine in the

    United States. Available at :http://nccam.nih.gov/health/whatiscam/.

    Accessed November 22, 2007

    http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=434http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=434http://nccam.nih.gov/health/whatiscam/http://nccam.nih.gov/health/whatiscam/http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=434http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=434
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    Daftar Pustaka

    9. Clegg DO, Reda DJ , Harris CL, Klein MA, O'DellJR, Hooper MM. Glucosamine, chondroitin sulfate,

    and the two in combination for painful knee

    osteoarthritis. N Engl J Med 2006;354:795-808.

    10. Turner RB, Bauer R, Woelkart K, Hulsey TC,Gangemi JD. An evaluation of Echinacea

    angustifolia in experimental rhinovirus infections.

    N Engl J Med 2005; 353: 341-8.

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    Daftar Pustaka

    11. Hypericum Depression Trial Study Group.Effect of Hypericum perforatum (St John's wort)

    in major depressive disorder: a randomized

    controlled trial. JAMA 2002;10:1807-14.

    12. Kwon YD, Pittler MH, Ernst E. Acupuncture forperipheral joint osteoarthritis : a systematic

    review and meta-analysis. Rheumatology

    2006;45:13317.

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    Daftar Pustaka

    13. Silverstein DD, Spiegel AD. Are physicians

    aware of the risks of alternative medicine? J Com

    Health 2001; 26 :159-74.

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